ArticleThe Plant cell2021
Ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains in hexaploid wheat in a dosage-dependent manner.
Article in The Plant cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 73 citations in OpenAlex.
- Increased grain weight conferred by GW2 mutations in wheat does not translate into yield gains in multi-year field trials of near-isogenic lines.Journal of experimental botany · 2026Article
- An Intronic Structural Variant in GhEBS1 Drives Cotton Fruit Size Divergence by Modulating Chromatin Accessibility and Gene Expression.Plant biotechnology journal · 2026Article
- Design and Deployment of a Regulation-Compliant Infrared Heating System for UK Field Trials.Plant-environment interactions (Hoboken, N.J.) · 2026Article
- Characterization and Fine Mapping ofPlants (Basel, Switzerland) · 2026Article
- Spatial transcriptomics identifies distinct domains regulating yield-component traits of the wheat ear.Science advances · 2026Article
- Regulation of spikelet number during wheat spike development.bioRxiv : the preprint server for biology · 2026Article
- Membrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials.Nature biotechnology · 2026Article
- Hidden gradients before form: a spatial transcriptomic atlas of wheat spike patterning.The Plant cell · 2026Article
- Spatial transcriptomics reveals expression gradients in developing wheat inflorescences at cellular resolution.The Plant cell · 2026Article
- Article
- Spatial and single-cell expression analyses reveal complex expression domains in early wheat spike development.Genome biology · 2025Article
- Natural variation in CHELATASE SUBUNIT I-A increases grain weight and enhances wheat yield.The Plant cell · 2025Article
- QTL analysis of spike traits and KASP marker validation for basal sterile spikelet number in wheat.BMC plant biology · 2025Article
- Article
- Decoupling the pleiotropic effects of VRT-A2 during reproductive development enhances wheat grain length and weight.The Plant cell · 2025Article
- Precise deletion, replacement and inversion of large DNA fragments in plants using dual prime editing.Nature plants · 2025Article
- Advances in genome editing in plants within an evolving regulatory landscape, with a focus on its application in wheat breeding.Journal of plant biochemistry and biotechnology · 2025Review
- Transcription factor VRT2 reinitiates vernalization when interrupted by warm temperatures in a temperate grass model.Plant physiology · 2024Article
- Introgression of chromosome 5P from Agropyron cristatum enhances grain weight in a wheat background.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Photoperiod-1 regulates the wheat inflorescence transcriptome to influence spikelet architecture and flowering time.Current biology : CB · 2024Article
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
Abstract
Flower development is an important determinant of grain yield in crops. In wheat (Triticum spp.), natural variation for the size of spikelet and floral organs is particularly evident in Triticum turgidum ssp. polonicum (also termed Triticum polonicum), a tetraploid subspecies of wheat with long glumes, lemmas, and grains. Using map-based cloning, we identified VEGETATIVE TO REPRODUCTIVE TRANSITION 2 (VRT2), which encodes a MADS-box transcription factor belonging to the SHORT VEGETATIVE PHASE family, as the gene underlying the T. polonicum long-glume (P1) locus. The causal P1 mutation is a sequence rearrangement in intron-1 that results in ectopic expression of the T. polonicum VRT-A2 allele. Based on allelic variation studies, we propose that the intron-1 mutation in VRT-A2 is the unique T. polonicum subspecies-defining polymorphism, which was later introduced into hexaploid wheat via natural hybridizations. Near-isogenic lines differing for the P1 locus revealed a gradient effect of P1 across spikelets and within florets. Transgenic lines of hexaploid wheat carrying the T. polonicum VRT-A2 allele show that expression levels of VRT-A2 are highly correlated with spike, glume, grain, and floral organ length. These results highlight how changes in expression profiles, through variation in cis-regulation, can affect agronomic traits in a dosage-dependent manner in polyploid crops.
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