ArticleEnvironmental health perspectives2021
Prenatal Exposure to Glyphosate and Its Environmental Degradate, Aminomethylphosphonic Acid (AMPA), and Preterm Birth: A Nested Case-Control Study in the PROTECT Cohort (Puerto Rico).
Article in Environmental health perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Urinary Glyphosate Concentrations among Pregnant Participants in a Randomized, Crossover Trial of Organic and Conventional Diets.Environmental health perspectives · 2023Trial
- Associations of glyphosate exposure in pregnancy with preterm birth: a longitudinal birth cohort study.Environmental pollution (Barking, Essex : 1987) · 2026Article
- Associations of glyphosate and aminomethylphosphonic acid (AMPA) concentrations with birth outcomes in pregnant women from the Midwestern U.S.International journal of hygiene and environmental health · 2026Article
- Construction of an Adverse Outcome Pathway Framework for Glyphosate-Induced Female Reproductive Toxicity Based on Toxicity Pathways.Environment & health (Washington, D.C.) · 2026Review
- Sex-specific cardiac remodeling and metabolic reprogramming in IUGR F2 fetuses following glyphosate or glyphosate-based herbicide exposure.Frontiers in toxicology · 2026Article
- Global Evidence on Monitoring Human Pesticide Exposure.Journal of xenobiotics · 2025Review
- Gestational urinary concentrations of glyphosate and aminomethylphosphonic acid in relation to preterm birth: the MIREC study.Journal of exposure science & environmental epidemiology · 2025Article
- Measured exposures to glyphosate in applicators and the general population: an updated review of the scientific literature since 2020.Pest management science · 2025Review
- Sociodemographic and dietary determinants of glyphosate exposure in a NYC-based pregnancy cohort.Environmental pollution (Barking, Essex : 1987) · 2024Article
- Characterization of pesticide exposures and their associations with asthma morbidity in a predominantly low-income urban pediatric cohort in Baltimore City.Environmental research · 2024Article
- Pesticide Exposures during Pregnancy and Health Outcomes in Latin America and the Caribbean: A Scoping Review of Human Observational Studies.Journal of health & pollution · 2024Review
- Article
- Gestational glyphosate exposure and early childhood neurodevelopment in a Puerto Rico birth cohort.Environmental research · 2024Article
- Glyphosate and a glyphosate-based herbicide dysregulate the epigenetic landscape of Homeobox A10 (Frontiers in toxicology · 2024Article
- The Effect of Pesticide Spray Season and Residential Proximity to Agriculture on Glyphosate Exposure among Pregnant People in Southern Idaho, 2021.Environmental health perspectives · 2023Article
- Perinatal health effects of herbicides exposures in the United States: the Heartland Study, a Midwestern birth cohort study.BMC public health · 2023Article
- Glyphosate exposure and preterm birth: A nested case-control pilot study.Reproductive toxicology (Elmsford, N.Y.) · 2023Article
- Exposure to glyphosate in the United States: Data from the 2013-2014 National Health and Nutrition Examination Survey.Environment international · 2022Article
- Glyphosate exposure in early pregnancy and reduced fetal growth: a prospective observational study of high-risk pregnancies.Environmental health : a global access science source · 2022Observational
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10 authors at 5 institutions in 2 countries.
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Abstract
backgroundGlyphosate (GLY) is the most heavily used herbicide in the world. Despite nearly ubiquitous exposure, few studies have examined prenatal GLY exposure and potentially adverse pregnancy outcomes. Preterm birth (PTB) is a risk factor for neonatal mortality and adverse health effects in childhood.
objectivesWe examined prenatal exposure to GLY and a highly persistent environmental degradate of GLY, aminomethylphosphonic acid (AMPA), and odds of PTB in a nested case-control study within the ongoing Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) pregnancy cohort in northern Puerto Rico.
methodsGLY and AMPA in urine samples collected at
resultsDetection rates in controls were 77.4% and 77.5% for GLY and 52.8% and 47.7% for AMPA, and geometric means (geometric standard deviations) were 0.44 (2.50) and 0.41 DISCUSSION: Urine GLY and AMPA levels in samples collected near the 26th week of pregnancy were associated with increased odds of PTB in this modestly sized nested case-control study. Given the widespread use of GLY, multiple potential sources of AMPA, and AMPA's persistence in the environment, as well as the potential for long-term adverse health effects in preterm infants, further investigation in other populations is warranted. https://doi.org/10.1289/EHP7295.
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