Evidence map›Paper›PMID 34008963›Full record

ArticleACS sensors2021

Development of a Soluble KIT Electrochemical Aptasensor for Cancer Theranostics.

Saeromi Chung, Jason K Sicklick, Partha Ray, Drew A Hall

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Therapeutic Potential of Aptamer-Protein Interactions.ACS pharmacology & translational science · 2022
    Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Saeromi ChungDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California 92093, United States.
Jason K SicklickDepartment of Surgery, Division of Surgical Oncology, Moores Cancer Center, University of California San Diego Health, San Diego, California 92093, United States.
Partha RayDepartment of Surgery, Division of Surgical Oncology, Moores Cancer Center, University of California San Diego Health, San Diego, California 92093, United States.ORCID 0000-0002-7075-5463
Drew A HallDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, California 92093, United States.ORCID 0000-0003-0674-074X
University of California San Diego · US

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
Targeting Drug-Resistant Cancer Stem Cell Niches of Gastrointestinal Stromal TumorR01CA226803 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SICKLICK, JASON KEITH · 2019 to 2023
$2.1M
Investigation of DNA Damaging Agents in GIST with Metabolic DysfunctionR01FD006334 · FDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SICKLICK, JASON KEITH · 2019 to 2021
$1.5M
Develop technology platform to transform the diagnosing, monitoring and treating of opioid use disordersR41DA044905 · NIDA · CARI HEALTH, INC. · PI SCHMIDLE, PATRIK · 2017 to 2017
$236k
FDA HHS R01 FD006334NCATS NIH HHS UL1 TR001442NCI NIH HHS R01 CA226803NIDA NIH HHS R41 DA044905
6 · The paper itself

Abstract

An electrochemical sensor based on a conformation-changing aptamer is reported to detect soluble KIT, a cancer biomarker, in human serum. The sensor was fabricated with a ferrocene-labeled aptamer (

Indexed as

Aptamers, NucleotideBiosensing TechniquesNeoplasmsElectrochemical TechniquesHumansPrecision MedicineAptamers, Nucleotideaptameraptasensorcancerelectrochemical sensorKITsquare-wave voltammetrytheranostics

Identifiers

PMID34008963
PMCPMC8785434
OpenAlexW3163548991

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.