Evidence map›Paper›PMID 34008713›Full record

ArticleArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2021

EFFICACY OF LOW-LEVEL LASER THERAPY ON FISTULA-IN-ANO TREATMENT.

Carlos Henrique Marques Dos Santos, Felipe Dos Santos Guimarães, Fernanda Helene Reis Barros, Guilherme Apolinário Laureano Leme, Lucas Dutra Madrid da Silva, Sandro Endrick de Oliveira Santos

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Carlos Henrique Marques Dos SantosColoproctology Department, University Hospital Maria Aparecida Pedrossian, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-1181-7329
Felipe Dos Santos GuimarãesAnhanguera-Uniderp University, Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-9177-7848
Fernanda Helene Reis BarrosAnhanguera-Uniderp University, Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-2590-2890
Guilherme Apolinário Laureano LemeColoproctology Department, University Hospital Maria Aparecida Pedrossian, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-6391-8666
Lucas Dutra Madrid da SilvaAnhanguera-Uniderp University, Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-0892-9418
Sandro Endrick de Oliveira SantosAnhanguera-Uniderp University, Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-3242-4081
Anhanguera-Uniderp University · BRUniversidade Federal de Mato Grosso do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFistulous area being A control and B laser group: Arrows indicate fistulous tract much thinner in B. Treating anal fistulae is still a great challenge due to the possibility of fecal incontinence after surgery and that the use of laser has been gaining space in medicine, including as an inducing method of healing.

aimTo evaluate the efficacy of low-level laser therapy on fistula-in-ano treatment in rats.

methodsFifteen male Wistar rats weighing approximately 250-300g were used, which were subjected to the anal fistula induction procedure and after 30 days were distributed into two groups: control group (CG, n=5) and laser group (LG, n=10) observed for another 30 days. In the CG no treatment was performed and, in the LG, low-level laser therapy was applied in fistulous tracts daily. The closure of the fistulous tract, the area of the remaining tract, the inflammatory infiltrate and vascular congestion were evaluated.

resultsThere was no complete closure of the tract in any of the animals. The mean area of the remaining tract was 847.2 µm2 in the CG and 248.5 µm2 in the LG (p=0.001). The mean inflammatory infiltrate score was 2.4 in the CG and 1.3 in the LG (p=0.0285), while in the evaluation of vascular congestion, 1.6 was observed in the CG and 0.6 in the LG (p=0.031).

conclusionsLow-level laser therapy was able to reduce the area of the fistulous tracts as well as decrease the inflammatory process and local vascular congestion.

Indexed as

Fecal IncontinenceLow-Level Light TherapyRectal FistulaAnal CanalAnimalsMaleRatsRats, WistarTreatment OutcomeWound Healing

Identifiers

PMID34008713
PMCPMC8121061
OpenAlexW3163284167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.