Evidence map›Paper›PMID 34008706›Full record

ArticleArquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery2021

RECURRENCE IN PN0 GASTRIC CANCER: RISK FACTORS IN THE OCCIDENT.

Karolyne Ernesto Luiz Nobre, Marina Alessandra Pereira, Marcus Fernando Kodama Pertille Ramos, Ulysses Ribeiro, Bruno Zilberstein, Ivan Cecconello, André Roncon Dias

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. HOSPITAL VOLUME, POSTOPERATIVE MORTALITY, AND COSTS AFTER GASTRECTOMY FOR GASTRIC CANCER IN COLOMBIA: IS THERE ANY ASSOCIATION?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
    Article
  4. FAILURE TO RESCUE AFTER GASTRECTOMY: A NEW INDICATOR OF SURGICAL QUALITY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
    Article
  5. SURGICAL TREATMENT IN CLINICAL STAGE IV GASTRIC CANCER: A COMPARISON OF DIFFERENT PROCEDURES AND SURVIVAL OUTCOMES.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Karolyne Ernesto Luiz NobreSchool of Medical Sciences, UNIFACISA, Medicine, Campina Grande, PB, Brazil.ORCID http://orcid.org/0000-0002-0497-7981
Marina Alessandra PereiraCancer Institute, Hospital das Clinicas, University of São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-6865-0988
Marcus Fernando Kodama Pertille RamosCancer Institute, Hospital das Clinicas, University of São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-0200-7858
Ulysses RibeiroCancer Institute, Hospital das Clinicas, University of São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1711-7347
Bruno ZilbersteinCancer Institute, Hospital das Clinicas, University of São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-1809-8558
Ivan CecconelloCancer Institute, Hospital das Clinicas, University of São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-3535-4170
André Roncon DiasCancer Institute, Hospital das Clinicas, University of São Paulo, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-3378-4916
Universidade de São Paulo · BRUnidade Integrada de Farmacologia e Gastroenterologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNearly 10% of node negative gastric cancer patients who underwent curative surgery have disease recurrence. Western data is extremely poor on this matter and identifying the risk factors that associate with relapse may allow new strategies to improve survival.

aimVerify the clinical and pathological characteristics that correlate with recurrence in node negative gastric cancer.

methodsAll gastric cancer patients submitted to gastrectomy between 2009 and 2019 at our institution and pathologically classified as N0 were considered. Their data were available in a prospective database. Inclusion criteria were: gastric adenocarcinoma, node negative, gastrectomy with curative intent, R0 resection. Main outcomes studied were: disease-free survival and overall survival.

resultsA total of 270 patients fulfilled the inclusion criteria. Mean age was 63-year-old and 155 were males. Subtotal gastrectomy and D2 lymphadenectomy were performed in 64% and 74.4%, respectively. Mean lymph node yield was 37.6. Early GC was present in 54.1% of the cases. Mean follow-up was 40.8 months and 19 (7%) patients relapsed. Disease-free survival and overall survival were 90.9% and 74.6%, respectively. Independent risk factors for worse disease-free survival were: total gastrectomy, lesion size ≥3.4 cm, higher pT status and <16 lymph nodes resected.

conclusionIn western gastric cancer pN0 patients submitted to gastrectomy, lymph node count <16, pT3-4 status, tumor size ≥3.4 cm, total gastrectomy and presence of lymphatic invasion, are all risk factors for disease relapse.

Indexed as

Stomach NeoplasmsFemaleGastrectomyHumansLymphatic MetastasisLymph Node ExcisionMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingRetrospective StudiesRisk Factors

Identifiers

PMID34008706
PMCPMC8121064
OpenAlexW3163657569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.