ArticleBone & joint research2021
Long-term patient-related quality of life after fracture-related infections of the long bones.
Article in Bone & joint research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 73 citations in OpenAlex.
- Trial
- Translation-driven design: development of an antibiotic-loaded hydrogel for the management of orthopaedic device-related infection.Bioactive materials · 2026Article
- Treatment gaps in osteoporosis care following recurrent fractures: a nationwide cohort study.Journal of comparative effectiveness research · 2026Article
- Long-term radiological and clinical outcomes after surgical treatment of non-union: a ten-year follow-up study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Impact of Infection Timing on Outcomes: A Comparative Study of Periprosthetic Joint and Fracture-Related Infections.Orthopaedic surgery · 2026Article
- Investigating long-term quality of life and depressive symptoms following fracture-related infection: a systematic review with meta-analysis of heterogeneous evidence.Journal of bone and joint infection · 2026Review
- Safety of locally applied antibiotics in orthopaedic trauma surgery: descriptive results from a prospective cohort study.Journal of bone and joint infection · 2026Article
- Twenty common errors in the prevention, diagnosis, and treatment of fracture-related infection (FRI).Journal of bone and joint infection · 2026Review
- Distinct Patient Characteristics and Risk Profiles in Upper vs. Lower Leg Fractures: Insights from a Comprehensive Cohort Study.Diagnostics (Basel, Switzerland) · 2025Article
- Life after bone infection: a retrospective comparison of quality of life in patients with periprosthetic joint infection and fracture-related infections.Journal of orthopaedic surgery and research · 2025Article
- A Comparison of Health-Related Quality of Life in Patients with Periprosthetic Joint Infection, Patients with Fracture-Related Infections and the General Population-A Multicenter Analysis of 384 Patients from the Section "Musculoskeletal Infections" of the German Society for Orthopaedics and Traumatology.Journal of clinical medicine · 2025Article
- Patients' quality of life and function evaluation after successful management of infected segmental bone defects with the induced membrane technique.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Poor consideration of tissue loading in randomised trials of MSC interventions for tendon pathology: A systematic review using the TIDieR framework.Journal of experimental orthopaedics · 2025Review
- Advancing cross-disciplinarity in bone and joint infection science using the COMBINE approach: an example from Denmark.Journal of bone and joint infection · 2025Article
- Fracture-Related Infection of the Proximal Femur - Diagnostics and Treatment.Geriatric orthopaedic surgery & rehabilitation · 2025Review
- Review
- Biofilm Formation, Antibiotic Resistance, and Infection (BARI): The Triangle of Death.Journal of clinical medicine · 2024Review
- Pathogens in FRI - Do bugs matter? - An analysis of FRI studies to assess your enemy.Journal of orthopaedics · 2024Article
- The surgical management of fracture-related infection. Surgical strategy selection and the need for early surgical intervention.Journal of orthopaedics · 2024Article
- Teaching potential of interdisciplinary meetings on osteoarticular infections for orthopaedic residents: Insights from a French reference center (CRIOAC).GMS journal for medical education · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsWe aimed to evaluate the long-term impact of fracture-related infection (FRI) on patients' physical health and psychological wellbeing. For this purpose, quality of life after successful surgical treatment of FRIs of long bones was assessed.
methodsA total of 37 patients treated between November 2009 and March 2019, with achieved eradication of infection and stable bone consolidation after long bone FRI, were included. Quality of life was evaluated with the EuroQol five-dimension questionnaire (EQ-5D) and German Short-Form 36 (SF-36) outcome instruments as well as with an International Classification of Diseases of the World Health Organization (ICD)-10 based symptom rating (ISR) and compared to normative data.
resultsWith a mean follow-up of 4.19 years (SD 2.7) after the last surgery, the mean SF-36 score was 40.1 (SD 14.6) regarding the physical health component and 48.7 (SD 5.1) regarding the mental health component, compared to German normative values of 48.4 (SD 9.2) (p < 0.001) and 50.9 (SD 8.8) (p = 0.143). The mean EQ-5D index reached 0.76 (SD 0.27) with a mean EQ-5D visual analogue scale (VAS) rating of 65.7 (SD 22.7) compared to reference scores of 0.88 (p < 0.001) and 72.9 (p < 0.001). Mean scores of the ISR did not reveal significant psychological symptom burden, while an individual analysis showed moderate to severe impairments in 21.6% (n = 8) of the patients.
conclusionEven a mean 4.2 years (SD 2.7) after surgically successful treatment of FRI of long bones, patients report significantly lower quality of life in comparison to normative data. Future clinical studies on FRIs should focus on patient-related outcome measures enabling best possible shared treatment decision-making. Prevention methods and interdisciplinary approaches should be implemented to improve the overall quality of life of FRI patients. Cite this article:
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