Evidence map›Paper›PMID 34008410›Full record

ArticleEpigenomics2021

Early-life stress induces genome-wide sex-dependent miRNA expression and correlation across limbic brain areas in rats.

Lauren A McKibben, Yogesh Dwivedi

Open access · hybridAbstract read
In one paragraph

Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. The Role of MicroRNA and Microbiota in Depression and Anxiety.Frontiers in behavioral neuroscience · 2022
    Review
  16. The miRNome of Depression.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lauren A McKibbenDepartment of Psychiatry & Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.ORCID 0000-0002-7307-6677
Yogesh DwivediDepartment of Psychiatry & Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.ORCID 0000-0002-5359-4717
University of Alabama at Birmingham · US

Funding

Plasma Exosomal MicroRNAs as Promising Novel Biomarkers for Suicidality and Treatment OutcomeR01MH107183 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DWIVEDI, YOGESH, SHELTON, RICHARD CHARLES · 2015 to 2019
$3.5M
Epitranscriptomic Mapping of Novel N6-Adenosine-based RNA Methylation in MDD BrainR01MH118884 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DWIVEDI, YOGESH · 2019 to 2023
$3.0M
MicroRNA Mapping in Major DepressionR01MH100616 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DWIVEDI, YOGESH · 2014 to 2019
$1.8M
Perturbed cell signaling network and suicide neurobiologyR01MH101890 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DWIVEDI, YOGESH · 2013 to 2017
$1.6M
Calcium Sensing Proteins in DepressionR01MH082802 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DWIVEDI, YOGESH · 2009 to 2013
$1.4M
MicroRNA Mediators of Early Life Stress Vulnerability and ResilienceR21MH112014 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DWIVEDI, YOGESH, SHELTON, RICHARD CHARLES · 2017 to 2018
$408k
NIMH NIH HHS R01 MH082802NIMH NIH HHS R01 MH100616NIMH NIH HHS R01 MH101890NIMH NIH HHS R01 MH107183NIMH NIH HHS R01 MH118884NIMH NIH HHS R21 MH112014
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersGene Expression RegulationAge FactorsAmygdalaAnimalsBehavior, AnimalBrainChromosome MappingCluster AnalysisComputational BiologyFemaleGene Regulatory NetworksHippocampusMaleMicroRNAsPrefrontal CortexBiomarkersMicroRNAsdepressionearly-life stressmaternal separationmiRNAssex differences

Identifiers

PMID34008410
PMCPMC8244583
OpenAlexW3163823451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.