Evidence map›Paper›PMID 34008050›Full record

ArticleCell and tissue research2021

NRF2-mediated signaling is a master regulator of transcription factors in bovine granulosa cells under oxidative stress condition.

Mohamed Omar Taqi, Mohammed Saeed-Zidane, Samuel Gebremedhn, Dessie Salilew-Wondim, Ernst Tholen, Christiane Neuhoff, Michael Hoelker, Karl Schellander, Dawit Tesfaye

Open access · hybridAbstract read
In one paragraph

Article in Cell and tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Antioxidants (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 4 countries.

Mohamed Omar TaqiInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Mohammed Saeed-ZidaneInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Samuel GebremedhnInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Dessie Salilew-WondimInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Ernst TholenInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Christiane NeuhoffInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Michael HoelkerInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Karl SchellanderInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany.
Dawit TesfayeInstitute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Bonn, Germany. Dawit.Tesfaye@colostate.edu.ORCID http://orcid.org/0000-0001-8166-0606
University of Bonn · DEFederal Foreign Office · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription factors (TFs) are known to be involved in regulating the expression of several classes of genes during folliculogenesis. However, the regulatory role of TFs during oxidative stress (OS) is not fully understood. The current study was aimed to investigate the regulation of the TFs in bovine granulosa cells (bGCs) during exposure to OS induced by H

Indexed as

AnimalsCattleFemaleGranulosa CellsNF-E2-Related Factor 2Oxidative StressSignal TransductionTranscription FactorsTransfectionNF-E2-Related Factor 2Transcription FactorsApoptosis and differentiationGranulosa cellsNRF2 signalingOxidative stressTranscription factors

Identifiers

PMID34008050
PMCPMC8526460
OpenAlexW3163300036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.