Evidence map›Paper›PMID 34008037›Full record

ReviewJournal of the Association for Research in Otolaryngology : JARO2021

Hearing Impairment and Cognition in an Aging World.

Danielle S Powell, Esther S Oh, Frank R Lin, Jennifer A Deal

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of the Association for Research in Otolaryngology : JARO, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Mutation Spectrum ofInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Hearing Care Within Diabetes Care: Strategies for Direct Inclusion.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  18. Article
  19. Article
  20. Experimental laboratory models as tools for understanding modifiable dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Danielle S PowellDepartment, of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. dpowel33@jhu.edu.ORCID 0000-0003-3447-4450
Esther S OhCochlear Center for Hearing and Public Health, Health, Johns Hopkins Bloomberg School of Public, Baltimore, MD, USA.
Frank R LinDepartment, of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Jennifer A DealDepartment, of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Johns Hopkins University · US

Funding

Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI JUAN TRONCOSO · 2020 to 2026
$29.3M
Novel Blood Biomarker of Alzheimer's disease Using Oral Glucose ToleranceR01AG057725 · NIA · JOHNS HOPKINS UNIVERSITY · PI OH, ESTHER SEUNGHEE · 2017 to 2021
$2.4M
Role and Mechanism of Hearing Impairment in Cognitive Decline and DementiaK01AG054693 · NIA · JOHNS HOPKINS UNIVERSITY · PI DEAL, JENNIFER ANNE · 2017 to 2022
$773k
NIA NIH HHS K01 AG054693NIA NIH HHS P30 AG066507NIA NIH HHS R01 AG057725
6 · The paper itself

Abstract

With the increasing number of older adults around the world, the overall number of dementia cases is expected to rise dramatically in the next 40 years. In 2020, nearly 6 million individuals in the USA were living with Alzheimer's disease, the most common type of dementia, with anticipated growth to nearly 14 million by year 2050. This increasing prevalence, coupled with high societal burden, makes prevention and intervention of dementia a medical and public health priority. As clinicians and researchers, we will continue to see more individuals with hearing loss with other comorbidities including dementia. Epidemiologic evidence suggests an association between hearing loss and increased risk of dementia, presenting opportunity for targeted intervention for hearing loss to play a fundamental role in dementia prevention. In this discussion, we summarize current research on the association between hearing loss and dementia and review potential casual mechanisms behind the association (e.g., sensory-deprivation hypothesis, information-degradation hypothesis, common cause). We emphasize key areas of research which might best inform our investigation of this potential casual association. These selected research priorities include examination of the causal mechanism, measurement of co-existing hearing loss and cognitive impairment, and potential of aural rehabilitation. Addressing these research gaps and how results are then translated for clinical use is paramount for dementia prevention and overall health of older adults.

Indexed as

DeafnessDementiaHearing LossAgedAgingCognitionHumanscognitive declinedementiahearing lossprevention

Identifiers

PMID34008037
PMCPMC8329135
OpenAlexW3160379000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.