Evidence map›Paper›PMID 34007839›Full record

ArticleFrontiers in physics2021

A Review of New High-Throughput Methods Designed for Fluorescence Lifetime Sensing From Cells and Tissues.

Aric Bitton, Jesus Sambrano, Samantha Valentino, Jessica P Houston

Abstract read
In one paragraph

Article in Frontiers in physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Towards accurate transcutaneous COBiosensors & bioelectronics · 2026
    Article
  2. Article
  3. Article
  4. Sexy ways: approaches to studying plant sex chromosomes.Journal of experimental botany · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aric Bitton *Department of Chemical and Materials Engineering, New Mexico State University, Las Cruces, NM, United States.
Jesus Sambrano *Department of Chemical and Materials Engineering, New Mexico State University, Las Cruces, NM, United States.
Samantha ValentinoDepartment of Chemical and Materials Engineering, New Mexico State University, Las Cruces, NM, United States.
Jessica P HoustonDepartment of Chemical and Materials Engineering, New Mexico State University, Las Cruces, NM, United States.

Funding

RISE PROGRAM AT NEW MEXICO STATE UNIVERSITYR25GM061222 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI HOUSTON, JESSICA PEREA, REDDI, LAKSHMI · 2000 to 2022
$21.3M
G-RISE at New Mexico State UniversityT32GM148394 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Jessica Perea Houston, Charles Bradley Shuster · 2023 to 2026
$2.1M
Microflow time-resolved cytometry for FRET and fluorescent protein developmentR01GM129859 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI HOUSTON, JESSICA PEREA · 2018 to 2021
$1.3M
Advanced approaches for biomedical measurements using time-resolved and micro-flow cytometryR35GM152076 · NIGMS · NEW MEXICO STATE UNIVERSITY LAS CRUCES · PI Jessica Perea Houston · 2024 to 2026
$1.1M
NIGMS NIH HHS R01 GM129859NIGMS NIH HHS R25 GM061222NIGMS NIH HHS R35 GM152076NIGMS NIH HHS T32 GM148394
6 · The paper itself

Abstract

Though much of the interest in fluorescence in the past has been on measuring spectral qualities such as wavelength and intensity, there are two other highly useful intrinsic properties of fluorescence: lifetime (or decay) and anisotropy (or polarization). Each has its own set of unique advantages, limitations, and challenges in detection when it comes to use in biological studies. This review will focus on the property of fluorescence lifetime, providing a brief background on instrumentation and theory, and examine the recent advancements and applications of measuring lifetime in the fields of high-throughput fluorescence lifetime imaging microscopy (HT-FLIM) and time-resolved flow cytometry (TRFC). In addition, the crossover of these two methods and their outlooks will be discussed.

Indexed as

flow cytometryfluorescence lifetimefluorescence lifetime imaging microscopyfrequency domainhigh-throughput approachestime domain

Identifiers

PMID34007839
PMCPMC8127321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.