ReviewAsia Pacific allergy2021
Impact and disease burden of chronic cough.
Review in Asia Pacific allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Non-pharmacological Management of Non-productive Chronic Cough in Adults: A Systematic Review.Frontiers in rehabilitation sciences · 2022Pooled it
- Efficacy and Safety of Zihua Wenfei Zhisou Granule in Treatment of Postinfectious Cough: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase II Clinical Trial.Chinese journal of integrative medicine · 2025Trial
- Safety and Pharmacokinetics of HRS-2261, a P2X3 Receptor Antagonist, in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study.Clinical pharmacokinetics · 2024Trial
- Traditional Chinese medicine combined with conventional Western medicine for chronic cough following respiratory infection in children: a systematic review and meta-analysis.Translational pediatrics · 2026Article
- KAAACI Consensus Document on the Goals and Standards of Chronic Cough Clinics in Korea: A Delphi Study.Allergy, asthma & immunology research · 2026Article
- Treatment response trajectories for speech pathology intervention in chronic cough.ERJ open research · 2026Article
- Relationship of breathlessness with social isolation and loneliness: a nationally representative cohort study of older adults in England.BMJ public health · 2026Article
- Telehealth group behavioural cough-suppression therapy for refractory chronic cough using a rolling enrolment model.ERJ open research · 2025Article
- Unbalanced Associations between Physical, Psychological, and Social Domains of the Leicester Cough Questionnaire: Network and Mediation Analyses.Tuberculosis and respiratory diseases · 2025Article
- Demographics, risk factors and prevalence of chronic cough in Asian general adult population: a narrative review.Journal of thoracic disease · 2025Review
- Long-Term Pulmonary Sequelae 5-14 Years After Protracted Bacterial Bronchitis in Early Childhood.Pediatric pulmonology · 2025Article
- Respiratory symptoms after coalmine fire and pandemic: A longitudinal analysis of the Hazelwood Health Study adult cohort.PLOS global public health · 2025Article
- An observational study to understand burden and cost of care in adults diagnosed with refractory chronic cough (RCC) or unexplained chronic cough (UCC).Respiratory research · 2024Observational
- Prevalence and disease burden of chronic cough in nine cities of China: an observational study.BMC pulmonary medicine · 2024Observational
- Formulation of international standards of Chinese medicine technology: clinical practice guide of Chinese medicine for cough.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Article
- Clinical and functional characteristics, possible causes, and impact of chronic cough in patients with cerebellar ataxia, neuropathy, and bilateral vestibular areflexia syndrome (CANVAS).Journal of neurology · 2024Article
- Research status of east Asian traditional medicine treatment for chronic cough: A scoping review.PloS one · 2024Article
- Cough Characteristics and Their Association Patterns According to Cough Etiology: A Network Analysis.Journal of clinical medicine · 2023Article
- Chronic Cough-Related Differences in Brain Morphometry in Adults: A Population-Based Study.Chest · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cough is an important physiological mechanism to protect the lower airways, but it is also one of the most common symptoms that lead patients to seek medical consultations. Chronic cough, usually defined by cough duration longer than 8 weeks in adults, is prevalent in the community and impairs quality of life in individual patients. There are several characteristics that may differentiate pathologic coughs from protective cough responses, including cough duration, frequency, hypersensitivity, impaired cough suppressibility, or treatment refractoriness. However, the impact of cough, or its perceived severity, is a sum of the patient's experience of coughing and is a factor that may finally define cough as a disease. Social isolation is a major impact of chronic cough, which is now worse due to the coronavirus disease 2019 pandemic and a widespread fear of cough as a source of contagion. Emotional impact and economic impact (medical cost, reduced work productivity, and job loss) are also important complications of chronic cough, and they interact in a vicious cycle, aggravated by social isolation and treatment failures. This paper is a narrative review that aims to address the impact and disease burden of chronic cough in adult patients. We review the literature, but also introduce the findings from recent qualitative interviews and the patients' experiences of the impact and burden of chronic cough and discuss unmet needs in these patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.