Evidence map›Paper›PMID 34007805›Full record

ReviewJournal of clinical and translational hepatology2021

Gut Microbiota in Metabolic-associated Fatty Liver Disease and in Other Chronic Metabolic Diseases.

Winston Hernández-Ceballos, Jacqueline Cordova-Gallardo, Nahum Mendez-Sanchez

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of clinical and translational hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Nonalcoholic Fatty Liver Disease and the Intestinal Microbiome: An Inseparable Link.Journal of clinical and translational hepatology · 2023
    Review
  9. Article
  10. Impact ofJournal of clinical and translational hepatology · 2023
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Comparison of gut microbiota in male MAFLD patients with varying liver stiffness.Frontiers in cellular and infection microbiology · 2022
    Article
  17. Article
  18. Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease.International journal of environmental research and public health · 2021
    Article
  19. The Immune System through the Lens of Alcohol Intake and Gut Microbiota.International journal of molecular sciences · 2021
    Review
  20. Drosophila as a Model for Microbiota Studies of Neurodegeneration.Journal of Alzheimer's disease : JAD · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Winston Hernández-CeballosPlan of Combined Studies in Medicine (PECEM-MD/PhD), Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-6779-5117
Jacqueline Cordova-GallardoDepartment of Hepatology, Service of Surgery and Obesity Clinic, General Hospital "Dr. Manuel Gea González", Mexico City, Mexico.ORCID https://orcid.org/0000-0002-4299-5400
Nahum Mendez-SanchezFaculty of Medicine. National Autonomous University of Mexico, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-5257-8048
Hospital General Dr. Manuel Gea Gonzalez · MXHospital Médica Sur · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiome plays a key role in the health-disease balance in the human body. Although its composition is unique for each person and tends to remain stable throughout lifetime, it has been shown that certain bacterial patterns may be determining factors in the onset of certain chronic metabolic diseases, such as type 2 diabetes mellitus (T2DM), obesity, metabolic-associated fatty liver disease (MAFLD), and metabolic syndrome. The gut-liver axis embodies the close relationship between the gut and the liver; disturbance of the normal gut microbiota, also known as dysbiosis, may lead to a cascade of mechanisms that modify the epithelial properties and facilitate bacterial translocation. Regulation of gut microbiota is fundamental to maintaining gut integrity, as well as the bile acids composition. In the present review, we summarize the current knowledge regarding the microbiota, bile acids composition and their association with MAFLD, obesity, T2DM and metabolic syndrome.

Indexed as

Bile acidsDysbiosisGut-liver axisGut microbiotaMetabolic-associated fatty liver diseaseMetabolic-associated steatohepatitis

Identifiers

PMID34007805
PMCPMC8111113
OpenAlexW3134187011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.