Evidence map›Paper›PMID 34007420›Full record

ReviewMediterranean journal of hematology and infectious diseases2021

Practical Recommendations for the Management of Patients with ITP During the COVID-19 Pandemic.

Francesco Rodeghiero, Silvia Cantoni, Giuseppe Carli, Monica Carpenedo, Valentina Carrai, Federico Chiurazzi, Valerio De Stefano, Cristina Santoro, Sergio Siragusa, Francesco Zaja and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Mediterranean journal of hematology and infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. The Differential Diagnosis of Thromobocytopenia.Deutsches Arzteblatt international · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. How we treat primary immune thrombocytopenia in adults.Journal of hematology & oncology · 2023
    Review
  8. Immune Thrombocytopenia Onset and Relapse During the COVID-19 Pandemic. A Monocenter Study.Mediterranean journal of hematology and infectious diseases · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Immune Thrombocytopenic Purpura Cases Following COVID-19 Vaccination.Mediterranean journal of hematology and infectious diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Francesco RodeghieroFondazione Progetto Ematologia, Vicenza.
Silvia CantoniDipartimento di Ematologia e Oncologia, Niguarda Cancer Center, ASST Grande Ospedale Metropolitano, Ospedale Niguarda, Milano.
Giuseppe CarliDivisione Ematologia, Ospedale S. Bortolo Vicenza, Vicenza.
Monica CarpenedoUO Ematologia e Trapianto, Azienda Ospedaliera "S. Gerardo", Monza.
Valentina CarraiA.O.U. Careggi - Ematologia, Firenze.
Federico ChiurazziDipartimento di Ematologia e Trapianto di Midollo, Ospedale Universitario Federico II, Napoli.
Valerio De StefanoDipartimento di Scienze Radiologiche ed Ematologiche, Sezione di Ematologia, Università Cattolica del Sacro Cuore - Fondazione Policlinico A. Gemelli IRCCS, Roma.
Cristina SantoroEmatologia, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma.
Sergio SiragusaDipartimento Promise, Università degli Studi di Palermo, Palermo.
Francesco ZajaDipartimento Clinico di Scienze Mediche, Chirurgiche e della Salute, Università degli Studi di Trieste, Trieste.
Nicola VianelliIstituto di Ematologia "Seràgnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Fondazione Progetto Ematologia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current COVID-19 pandemic requires revisiting our current approach to major blood disorders, including ITP (Immune Thrombocytopenia), stirring up the production of several disease-specific practical guidelines. This report describes an updated version of consensus-based practical guidelines on the management of ITP, adapted to the Italian health system and social context. It highlights the role of the hematologist in offering guidance for choosing differentiated approaches in relation to specific circumstances and is intended to provide them with a useful tool for sharing the decision-making process with their patients. Probably, the greatest risk to avoid for a patient with suspected, ongoing or relapsed ITP - that is not severe enough to place him or her at risk for major bleeding - is to be infected in non-hospital and hospital healthcare settings. This risk must be carefully considered when adapting the diagnostic and therapeutic approach. More in detail, the document first addresses the appropriate management for COVID-19 negative patients with newly diagnosed ITP or who experience a relapse of previous ITP, according to first and second lines of treatment and then the management of COVID-19 positive patients according to their severity, from paucisymptomatic to those requiring admission to Intensive Cure Units (ICU). The pros and cons of the different treatments required to correct platelet count are discussed, as are some specific situations, including chronic ITP, splenectomy, thromboembolic complication and anti COVID-19 vaccination.

Indexed as

COVID-19Immune thrombocytopeniaITPPractical recommendations

Identifiers

PMID34007420
PMCPMC8114883
OpenAlexW3157069423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.