Evidence map›Paper›PMID 34007404›Full record

ReviewOxidative medicine and cellular longevity2021

Pyroptosis: A New Frontier in Kidney Diseases.

Ke-Jia Zhang, Qi Wu, Shi-Min Jiang, Lei Ding, Chao-Xia Liu, Ming Xu, Ying Wang, Yao Zhou, Li Li

Abstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Trial
  2. Role of pyroptosis in melanoma: Molecular mechanisms and therapeutic potentials.Apoptosis : an international journal on programmed cell death · 2026
    Review
  3. Article
  4. The roles of free-fatty acid receptors in the pathophysiology of renal disorders.The Journal of pharmacology and experimental therapeutics · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Role of gasdermins in chronic kidney disease.Frontiers in immunology · 2025
    Review
  11. Article
  12. Review
  13. Research Progress of Regulatory Cell Death in Coronary Microembolization.International journal of medical sciences · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ke-Jia ZhangDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-6970-8571
Qi WuDepartment of Physiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-0537-6467
Shi-Min JiangDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-1795-8587
Lei DingDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0003-4680-1180
Chao-Xia LiuDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0003-0072-1361
Ming XuDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-6813-5361
Ying WangDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-1339-8439
Yao ZhouDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0002-2845-6339
Li LiDepartment of Pathophysiology, Xuzhou Medical University, Xuzhou 221009, China.ORCID https://orcid.org/0000-0001-9461-596X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyroptosis is a pattern of programmed cell death that significantly differs from apoptosis and autophagy in terms of cell morphology and function. The process of pyroptosis is characterized predominantly by the formation of gasdermin protein family-mediated membrane perforation, cell collapse, and the release of inflammatory factors, including IL-1

Indexed as

AnimalsDisease Models, AnimalHumansKidney DiseasesMicePyroptosis

Identifiers

PMID34007404
PMCPMC8102120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.