Evidence map›Paper›PMID 34007403›Full record

ReviewOxidative medicine and cellular longevity2021

The Cross-Link between Ferroptosis and Kidney Diseases.

Jingyu Wang, Yi Liu, Yaqing Wang, Li Sun

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 108 citations in OpenAlex.

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  14. AlClFrontiers in toxicology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jingyu WangDepartment of Nephrology, The First Affiliated Hospital of China Medical University, Shenyang, 110000 Liaoning Province, China.ORCID https://orcid.org/0000-0003-1453-9587
Yi LiuDepartment of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan Province, China.
Yaqing WangDepartment of Nephrology, The First Affiliated Hospital of China Medical University, Shenyang, 110000 Liaoning Province, China.
Li SunDepartment of Nephrology, The First Affiliated Hospital of China Medical University, Shenyang, 110000 Liaoning Province, China.ORCID https://orcid.org/0000-0002-9682-990X
First Hospital of China Medical University · CNAffiliated Hospital of North Sichuan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders of the kidney in various etiologies, which significantly affect human survival and social wealth. Nephropathies are often accompanied by various forms of cell death and complex microenvironments. In recent decades, the study of kidney diseases and the traditional forms of cell death have improved. Nontraditional forms of cell death, represented by ferroptosis and necroptosis, have been discovered in the field of kidney diseases, which have reshuffled the role of traditional cell death in nephropathies. Although interactions between ferroptosis and acute kidney injury (AKI) have been continuously explored, studies on ferroptosis and chronic kidney disease (CKD) remain limited. Here, we have reviewed the therapeutic significance of ferroptosis in AKI and anticipated the curative potential of ferroptosis for CKD in the hope of providing insights into ferroptosis and CKD.

Indexed as

AnimalsDisease Models, AnimalFerroptosisHumansMiceRenal Insufficiency, Chronic

Identifiers

PMID34007403
PMCPMC8110383
OpenAlexW3157320378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.