Evidence map›Paper›PMID 34007275›Full record

ArticleJournal of oncology2021

Efficacy and Cost-Benefit Analysis of Magnetic Resonance Imaging in the Follow-Up of Soft Tissue Sarcomas of the Extremities and Trunk.

Daniel Kraus, Felix Oettinger, Jurij Kiefer, Holger Bannasch, G Björn Stark, Filip Simunovic

Abstract read
In one paragraph

Article in Journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel Kraus *Department of Plastic and Hand Surgery, Freiburg University Medical Center, Freiburg 79106, Germany.ORCID https://orcid.org/0000-0002-2229-5036
Felix Oettinger *Department of Plastic and Hand Surgery, Freiburg University Medical Center, Freiburg 79106, Germany.
Jurij KieferDepartment of Plastic and Hand Surgery, Freiburg University Medical Center, Freiburg 79106, Germany.ORCID https://orcid.org/0000-0002-1008-4522
Holger BannaschDepartment of Plastic, Hand und Aesthetic Surgery, Schwarzwald-Baar-Klinikum Donaueschingen, Donaueschingen 78166, Germany.
G Björn StarkDepartment of Plastic and Hand Surgery, Freiburg University Medical Center, Freiburg 79106, Germany.
Filip SimunovicDepartment of Plastic and Hand Surgery, Freiburg University Medical Center, Freiburg 79106, Germany.ORCID https://orcid.org/0000-0003-1755-5734

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no consensus regarding follow-up after soft tissue sarcoma (STS) treatment. This study examines the efficacy and the cost-benefit of MRI imaging for discovering recurrence. A retrospective analysis was performed, collecting data on patient demography, tumor characteristics, treatment, and follow-up. Imaging was correlated to the clinical course, and sensitivity, specificity, and predictive values were calculated. The number needed to screen and costs of finding recurrence are reported. Amongst 216 sarcomas, 73 (35%) exhibited local recurrence during a follow-up of 5.3 ± 3.5 years. 173 entities had complete MRI follow-up with 58 (34%) local recurrences. Thirty-three (57%) were discovered by MRI, 8 (14%) by clinical presentation, and 17 (29%) simultaneously. There was a sensitivity of 100.00%, a specificity of 89%, a positive predictive value of 32%, and a negative predictive value of 100% for detecting local recurrence with MRI. Our data confirm the modalities and intervals proposed by the German guidelines for sarcoma care. The recommended MRI intervals should not be extended. MRI is more cost-effective than clinical examination; still, both modalities should be performed together to discover the maximum number of recurrences.

Identifiers

PMID34007275
PMCPMC8100420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.