ArticleInternational journal of general medicine2021
Breast-Feeding is Not a Risk Factor of Mother-to-Child Transmission of Hepatitis B Virus.
Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- [Chinese practice guidelines for the prevention and treatment of mother-to-child transmission of hepatitis B virus (version 2024)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024Guideline
- Virucidal Efficacy of Holder Pasteurization of Breast Milk in a Portable Device.Pathogens (Basel, Switzerland) · 2026Article
- Redefining MTCT prevention strategies toward HBV elimination: Editorial on "Factors associated with hepatitis B mother-to-child transmission in a national prevention program".Clinical and molecular hepatology · 2026Article
- Breastfeeding practices among hepatitis b-infected mothers: a prospective cohort study.BMC pregnancy and childbirth · 2026Article
- Factors influencing breastfeeding failure in mothers with hepatitis B infection: a qualitative study.Frontiers in nutrition · 2026Article
- Elective cesarean section and bottle-feeding do not reduce infection of hepatitis B in infants of high viremic mothers: a retrospective study.BMC pregnancy and childbirth · 2025Article
- Chinese clinical practice guidelines for the prevention and treatment of mother-to-child transmission of hepatitis B virus (version 2024).Infectious diseases & immunity · 2025Article
- Chinese Clinical Practice Guidelines for the Prevention and Treatment of Mother-to-child Transmission of Hepatitis B Virus (Version 2024).Journal of clinical and translational hepatology · 2024Article
- Identifying Childhood Risk Factors for Hepatitis B with a Focus on Vertical Transmission.Diseases (Basel, Switzerland) · 2024Article
- Results of mother-to-child transmission in hepatitis B-positive mothers who underwent amniocentesis.BMC infectious diseases · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims at researching the content of hepatitis B virus (HBV) DNA in the breast milk of the mothers carrying HBV and investigating the effects of different feeding methods on mother-to-child transmission (MTCT) of HBV.
methodsAll infants were voluntarily chosen by their mothers and divided into breast-feeding group and formula-feeding group, which were divided into three subgroups, respectively: HBV-DNA negative (HBV-) group, low viral load (LVL) group and high viral load (HVL) group.
resultsHBV load in colostrum and mature milk were both significantly lower than in serum (P < 0.001). The positive rate of HBV-DNA in colostrum was positively correlated with HBV load in serum, significantly higher than that of the HBV-Group in colostrum in the LVL Group (P < 0.05), and the HVL Group was significantly higher than the LVL Group (P < 0.001). The analysis of risk factors of HBV infection in infants showed that breast-feeding and HBsAg positive in colostrum did not increase the risks of HBV infection of infants (P > 0.05).
conclusionBreast-feeding is safe for infants with HBV-infected mothers who receive active immunization combined with passive immunization. As well, breast-feeding will neither increase the risks of HBV infection for infants nor weaken their immunity to HBV. However, breast-feeding shall be cautiously applied to pregnant women with high viral load.
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