Evidence map›Paper›PMID 34007198›Full record

ArticleClinical, cosmetic and investigational dermatology2021

Seasonal Variation of Psoriasis and Its Impact in the Therapeutic Management: A Retrospective Study on Chinese Patients.

Xuanwei Zheng, Qiaolin Wang, Yan Luo, Wenhua Lu, Liping Jin, Menglin Chen, Wu Zhu, Yehong Kuang

Open access · goldAbstract read
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  5. Impact ofJournal of clinical medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Xuanwei Zheng *Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Qiaolin Wang *Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.ORCID 0000-0003-1397-6304
Yan LuoDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Wenhua LuDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Liping JinDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Menglin ChenDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Wu ZhuDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.ORCID 0000-0002-3645-7059
Yehong KuangDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, People's Republic of China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe seasonal patterns of psoriasis have been observed in previous studies. However, no published data indicated the risk factors associated with the seasonal variation. PURPOSE: This study aimed to investigate potentially related factors associated with seasonal pattern of psoriasis and provide possible implications for alleviating psoriasis in clinical practice. PATIENTS AND

methodsThe retrospective study was conducted in Chinese patients with psoriasis. Demographic and clinical information were collected. Multivariable logistic regression analyses (calculating adjusted odds ratios [AORs]) were used to analyze data.

resultsWe continually enrolled 2270 patients (1496 males and 774 females) with psoriasis based on inclusion criteria. Disease duration (AOR=1.06, 95% CI: 1.05-1.07), hyperlipidemia (AOR=1.77, 95% CI: 1.06-2.98) and smoking (AOR=1.40, 95% CI: 1.17-1.68) were significantly associated with severe psoriasis in autumn/winter. Age (AOR=0.98, 95% CI:0.97-0.99) and occupations with more sunlight exposure (AOR=0.78, 95% CI: 0.61-0.99) were negatively associated with the seasonal aggravation. Subgroup analysis showed that occupations with more sunlight exposure (AOR=0.64, 95% CI: 0.43-0.94) were protective factors only in late-onset psoriasis but not early-onset, while smoking (AOR=1.39, 95% CI: 1.11-1.74) was risk factor in the early-onset psoriasis.

conclusionPsoriatic patients who had occupation with more sunlight exposure were less likely to report aggravation of psoriasis in autumn/winter. On the contrary, smoking and hyperlipidemia were positively associated with the seasonal aggravation. Additional prospective study is needed to identify the causality.

Indexed as

occupational exposurepsoriasisseasonal variationsmokingultravioletweather

Identifiers

PMID34007198
PMCPMC8121268
OpenAlexW3160048133

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.