Evidence map›Paper›PMID 34006978›Full record

ArticleScientific reports2021

Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices.

Mara Yone D Fernandes, Fernando Dobrachinski, Henrique B Silva, João Pedro Lopes, Francisco Q Gonçalves, Felix A A Soares, Lisiane O Porciúncula, Geanne M Andrade, Rodrigo A Cunha, Angelo R Tomé

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Mara Yone D FernandesCNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Fernando DobrachinskiCNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Henrique B SilvaCNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
João Pedro LopesCNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Francisco Q GonçalvesCNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Felix A A SoaresCentro de Ciências Naturais E Exatas, Departamento de Bioquímica E Biologia Molecular, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Lisiane O PorciúnculaDepartamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Geanne M AndradeDepartment of Physiology and Pharmacology, Faculty of Medicine, Center for Research and Drug Development (NPDM), Federal University of Ceará, Fortaleza, Brazil.
Rodrigo A CunhaCNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal. cunharod@gmail.com.
Angelo R ToméCNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
University of Coimbra · PTUniversidade Federal de Santa Maria · BRUniversidade Federal do Ceará · BRUniversidade Federal do Rio Grande · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increased healthspan afforded by coffee intake provides novel opportunities to identify new therapeutic strategies. Caffeine has been proposed to afford benefits through adenosine A

Indexed as

Alzheimer DiseaseAnimalsChlorogenic AcidDisease Models, AnimalHippocampusIn Vitro TechniquesMaleMiceMice, Inbred C57BLNeuronal PlasticityNeuroprotective AgentsNeurotransmitter AgentsSynaptic TransmissionChlorogenic AcidNeuroprotective AgentsNeurotransmitter Agents

Identifiers

PMID34006978
PMCPMC8131611
OpenAlexW3163792070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.