SynthesisBritish journal of cancer2021
Fruit and vegetable consumption and incident breast cancer: a systematic review and meta-analysis of prospective studies.
Synthesis in British journal of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Sustainable dietary recommendations for the Spanish population.European journal of clinical nutrition · 2026Pooled it
- Adolescent Dietary Intake and Breast Cancer in Adulthood: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- Pooled it
- Dietary factors associated with breast cancer among women in Ethiopia: a systematic review and meta-analysis of case-control studies.Frontiers in nutrition · 2025Pooled it
- Dietary intake of tomato and lycopene, blood levels of lycopene, and risk of total and specific cancers in adults: a systematic review and dose-response meta-analysis of prospective cohort studies.Frontiers in nutrition · 2025Pooled it
- The Association between Circulating Carotenoids and Risk of Breast Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- Consumption of fruits and vegetables among adolescents in Arab Countries: a systematic review.The international journal of behavioral nutrition and physical activity · 2023Pooled it
- Healthy dietary patterns, foods, and risk of glioma: A systematic review and meta-analysis of observational studies.Frontiers in nutrition · 2022Pooled it
- Trial
- Examining Demographic Variables Associated with Fruit and Vegetable Intake and Skin Yellowness.Nutrients · 2026Article
- Real-World Evidence for Breast Cancer Risk Stratification: Insights from the P.I.N.K. Study.Cancers · 2026Article
- The Fortification of Fruit Mousses with Encapsulated Bioactive Compounds in a Potato Starch Matrix as an Example of Novel Functional Foods.International journal of molecular sciences · 2026Article
- Article
- Dietary carotenoids and breast cancer risk: evidence from a large population-based incident case-control study.Nutrition & metabolism · 2025Article
- Whole Fruits Versus 100% Fruit Juice: Revisiting the Evidence and Its Implications for US Healthy Dietary Recommendations.Nutrition bulletin · 2025Review
- Review
- Breast cancer: pathogenesis and treatments.Signal transduction and targeted therapy · 2025Review
- Gender, residence, and socioeconomic differences in the relationship of nutrition literacy with vegetable and fruit intake in adults.Frontiers in nutrition · 2025Article
- Association of sweetened beverage intake with incident risk of breast cancer: a prospective cohort study.Frontiers in nutrition · 2025Article
- From data to decisions: a paradigm shift in fruit agriculture through the integration of multi-omics, modern phenotyping, and cutting-edge bioinformatic tools.Frontiers in plant science · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe conducted a systematic review and meta-analysis of prospective studies to clarify the relation of fruit and vegetable consumption with incident breast cancer.
methodsWe searched systematically PubMed and EMBASE databases up to November 2020 to include prospective studies that reported the association of fruit and vegetable consumption with incident breast cancer. The pooled relative risks (RRs) and 95% confidence intervals (CIs) were calculated for the highest versus the lowest category of total fruit and vegetable, total fruit and total vegetable consumption, as well as fruit juice and subgroups of vegetables in relation to breast cancer incidence, using a random-effect model.
resultsTotal fruit and vegetable consumption was associated with lower overall (RR = 0.91, 95% CI = 0.87-0.95) and postmenopausal breast cancer risk (RR = 0.88, 95% CI = 0.79-0.99). Total fruit consumption was associated with lower overall (RR = 0.93, 95% CI = 0.88-0.99) and postmenopausal breast cancer risk (RR = 0.93, 95% CI = 0.87-0.99). Total fruit and vegetable intake were associated with 11% and 26% lower risk of oestrogen- and progesterone-receptor-positive (ER+/PR+) and -negative (ER-/PR-) breast cancer, respectively. Total vegetable consumption was associated with 27% lower risk of ER-/PR- breast cancer. Fruit juice consumption was associated with increased overall breast cancer risk (RR = 1.04, 95% CI = 1.01-1.07). We did not find significant associations for subgroups of vegetable intake and breast cancer risk.
conclusionsThese findings suggest that high total fruit and vegetable consumption are associated with reduced risk of overall, postmenopausal, ER+/PR+ and ER-/PR- breast cancer.
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