Evidence map›Paper›PMID 34006910›Full record

ArticleScientific reports2021

A deep learning model for detection of cervical spinal cord compression in MRI scans.

Zamir Merali, Justin Z Wang, Jetan H Badhiwala, Christopher D Witiw, Jefferson R Wilson, Michael G Fehlings

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05099627 (A Point-of-care Machine Learning Model and Scoring System for the Early Diagnosis and Prediction of Treatment Outcome in Patients With Cervical Myelopathy), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05099627 unknown statusnot on this map

A Point-of-care Machine Learning Model and Scoring System for the Early Diagnosis and Prediction of Treatment Outcome in Patients With Cervical Myelopathy: an Ambispective Cohort Study.

TypeobservationalSponsorImperial College Healthcare NHS TrustRan2021 to 2022Enrolled300ConditionsCervical MyelopathyArmsThe questionnaire "Cervical myelopathy treatment outcome questionnaire", The retrospective questionnaire "CSM early diagnosis questionnaire", JOACMEQ questionnaire and mJOA
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  4. ShuffleLeNet architecture for spinal cord injury classification and level detection.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  7. ShPCFHNet: shepherd parallel convolutional forward harmonic net for spinal cord injury detection using CT images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zamir MeraliDivision of Neurosurgery, Department of Surgery, University of Toronto, 149 College Street, Toronto, ON, M5T 1P5, Canada.
Justin Z WangDivision of Neurosurgery, Department of Surgery, University of Toronto, 149 College Street, Toronto, ON, M5T 1P5, Canada.
Jetan H BadhiwalaDivision of Neurosurgery, Department of Surgery, University of Toronto, 149 College Street, Toronto, ON, M5T 1P5, Canada.
Christopher D WitiwDivision of Neurosurgery, Department of Surgery, University of Toronto, 149 College Street, Toronto, ON, M5T 1P5, Canada.
Jefferson R WilsonDivision of Neurosurgery, Department of Surgery, University of Toronto, 149 College Street, Toronto, ON, M5T 1P5, Canada.
Michael G FehlingsDivision of Neurosurgery, Department of Surgery, University of Toronto, 149 College Street, Toronto, ON, M5T 1P5, Canada. Michael.Fehlings@uhn.ca.
University of Toronto · CASt. Michael's Hospital · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic Resonance Imaging (MRI) evidence of spinal cord compression plays a central role in the diagnosis of degenerative cervical myelopathy (DCM). There is growing recognition that deep learning models may assist in addressing the increasing volume of medical imaging data and provide initial interpretation of images gathered in a primary-care setting. We aimed to develop and validate a deep learning model for detection of cervical spinal cord compression in MRI scans. Patients undergoing surgery for DCM as a part of the AO Spine CSM-NA or CSM-I prospective cohort studies were included in our study. Patients were divided into a training/validation or holdout dataset. Images were labelled by two specialist physicians. We trained a deep convolutional neural network using images from the training/validation dataset and assessed model performance on the holdout dataset. The training/validation cohort included 201 patients with 6588 images and the holdout dataset included 88 patients with 2991 images. On the holdout dataset the deep learning model achieved an overall AUC of 0.94, sensitivity of 0.88, specificity of 0.89, and f1-score of 0.82. This model could improve the efficiency and objectivity of the interpretation of cervical spine MRI scans.

Indexed as

Deep LearningNeural Networks, ComputerCervical VertebraeCohort StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedReproducibility of ResultsSensitivity and SpecificitySpinal Cord Compression

Identifiers

PMID34006910
PMCPMC8131597
OpenAlexW3162804940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.