Evidence map›Paper›PMID 34006841›Full record

ArticleNature communications2021

CD8

Luca Hensen, Patricia T Illing, E Bridie Clemens, Thi H O Nguyen, Marios Koutsakos, Carolien E van de Sandt, Nicole A Mifsud, Andrea T Nguyen, Christopher Szeto, Brendon Y Chua and 26 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Multivariate Host-Pathogen Interactions Driving Heterogeneous Viral Shedding and CD8medRxiv : the preprint server for health sciences · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. CD8Nature communications · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 13 institutions in 3 countries.

Luca Hensen *Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0001-8467-8537
Patricia T Illing *Department of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.ORCID http://orcid.org/0000-0002-3870-0796
E Bridie Clemens *Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Thi H O NguyenDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-9294-7693
Marios KoutsakosDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Carolien E van de SandtDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-4155-7433
Nicole A MifsudDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.ORCID http://orcid.org/0000-0001-8647-2102
Andrea T NguyenDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Christopher SzetoDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.ORCID http://orcid.org/0000-0003-3784-5210
Brendon Y ChuaDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Hanim HalimDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Simone RizzettoSchool of Medical Sciences and The Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.ORCID http://orcid.org/0000-0003-3881-8759
Fabio LucianiSchool of Medical Sciences and The Kirby Institute, UNSW Sydney, Sydney, NSW, Australia.
Liyen LohDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-1676-0579
Emma J GrantDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Phillipa M SaundersDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-0813-7752
Andrew G BrooksDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-4085-9683
Steve RockmanDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Tom C KotsimbosDepartment of Allergy, Immunology and Respiratory Medicine, The Alfred Hospital, Melbourne, VIC, Australia.
Allen C ChengSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Michael RichardsVictorian Infectious Diseases Service, The Royal Melbourne Hospital, and Doherty Department University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Glen P WestallLung Transplant Unit, Alfred Hospital, Melbourne, VIC, Australia.
Linda M WakimDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.
Thomas LoudovarisImmunology and Diabetes Unit, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.
Stuart I ManneringImmunology and Diabetes Unit, St Vincent's Institute of Medical Research, Fitzroy, VIC, Australia.ORCID http://orcid.org/0000-0003-3497-3559
Michael ElliottSydney Medical School, University of Sydney, Sydney, NSW, Australia.
Stuart G TangyeImmunology Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.ORCID http://orcid.org/0000-0002-5360-5180
David C JacksonDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0001-7255-270X
Katie L FlanaganTasmanian Vaccine Trial Centre, Launceston General Hospital, Launceston, TAS, Australia.ORCID http://orcid.org/0000-0002-1575-1953
Jamie RossjohnDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.ORCID http://orcid.org/0000-0002-2020-7522
Stephanie GrasDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Jane DaviesMenzies School of Health Research, Darwin, NT, Australia.
Adrian MillerIndigenous Engagement, CQUniversity, Townsville, Australia.
Steven Y C TongVictorian Infectious Diseases Service, The Royal Melbourne Hospital, and Doherty Department University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia.ORCID http://orcid.org/0000-0002-1368-8356
Anthony W PurcellDepartment of Biochemistry and Molecular Biology & Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.ORCID http://orcid.org/0000-0003-0532-8331
Katherine KedzierskaDepartment of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia. kkedz@unimelb.edu.au.ORCID http://orcid.org/0000-0001-6141-335X
The University of Melbourne · AUAustralian Regenerative Medicine Institute · AUAustralian Research Council · AUSt Vincents Institute of Medical Research · AUThe Alfred Hospital · AUThe Royal Melbourne Hospital · AUUNSW Sydney · AUAlfred Health · AUCentral Queensland University · AUGarvan Institute of Medical Research · AUMenzies School of Health Research · AUThe University of Sydney · AUUniversity of Tasmania · AU

Funding

Household Respiratory Virus SARS-CoV-2 Transmission and Immunity Sub-Study (HRTS)U01AI144616 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GORDON, AUBREE L, THOMAS, PAUL G. · 2019 to 2025
$43.7M
NIAID NIH HHS U01 AI144616
6 · The paper itself

Abstract

Indigenous people worldwide are at high risk of developing severe influenza disease. HLA-A*24:02 allele, highly prevalent in Indigenous populations, is associated with influenza-induced mortality, although the basis for this association is unclear. Here, we define CD8

Indexed as

AdultAllelesAmino Acid SequenceAnimalsAustraliaCD8-Positive T-LymphocytesCells, CulturedDogsEpitopes, T-LymphocyteFemaleGene FrequencyHLA-A24 AntigenHumansIndigenous PeoplesInfluenza A virusInfluenza B virusEpitopes, T-LymphocyteHLA-A*24:02 antigenHLA-A24 Antigen

Identifiers

PMID34006841
PMCPMC8132304
OpenAlexW3163762505

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.