Evidence map›Paper›PMID 34006661›Full record

ArticlemBio2021

Circadian Clock Control of Translation Initiation Factor eIF2α Activity Requires eIF2γ-Dependent Recruitment of Rhythmic PPP-1 Phosphatase in

Zhaolan Ding, Teresa M Lamb, Ahmad Boukhris, Rachel Porter, Deborah Bell-Pedersen

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Cell surface (Amsterdam, Netherlands) · 2026
    Article
  3. Article
  4. A daily cycle of White Collar Complex dephosphorylation sustains circadian rhythmicity inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Circadian Control of Protein Synthesis.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhaolan DingDepartment of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA.
Teresa M LambDepartment of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA.
Ahmad BoukhrisDepartment of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA.
Rachel PorterDepartment of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA.
Deborah Bell-PedersenDepartment of Biology and Center for Biological Clocks Research, Texas A&M University, College Station, Texas, USA dpedersen@bio.tamu.edu.
Texas A&M University · US

Funding

Mechanisms of Circadian Clock Control of mRNA TranslationR35GM126966 · NIGMS · TEXAS A&M UNIVERSITY · PI Deborah Bell-Pedersen · 2018 to 2026
$6.6M
Molecular Genetic Analysis of Fungal Circadian RythmsR01GM058529 · NIGMS · TEXAS A&M UNIVERSITY SYSTEM · PI BELL-PEDERSEN, DEBORAH · 1999 to 2017
$4.6M
NIGMS NIH HHS R01 GM058529NIGMS NIH HHS R35 GM126966
6 · The paper itself

Abstract

The circadian clock controls the phosphorylation and activity of eukaryotic translation initiation factor 2α (eIF2α). In

Indexed as

Circadian ClocksEukaryotic Initiation Factor-2Fungal ProteinsNeurospora crassaPhosphorylationProtein BiosynthesisProtein Phosphatase 1Eukaryotic Initiation Factor-2Fungal ProteinsProtein Phosphatase 1circadian clockeIF2αeIF2γNeurospora crassaphosphatasePPP-1translation initiation

Identifiers

PMID34006661
PMCPMC8262944
OpenAlexW3161685858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.