Evidence map›Paper›PMID 34006651›Full record

ArticlemBio2021

Influence of the Alternative Sigma Factor RpoN on Global Gene Expression and Carbon Catabolism in Enterococcus faecalis V583.

Erica C Keffeler, Vijayalakshmi S Iyer, Srivatsan Parthasarathy, Matthew M Ramsey, Matthew J Gorman, Theresa L Barke, Sriram Varahan, Sally Olson, Michael S Gilmore, Zakria H Abdullahi and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. ProPr54 web server: predicting σNAR genomics and bioinformatics · 2025
    Article
  5. Article
  6. The sigma factor σFrontiers in microbiology · 2025
    Article
  7. Article
  8. Article
  9. Metabolism of Poly-β1,4-Journal of bacteriology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Erica C Keffeler *Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Vijayalakshmi S Iyer *Division of Biology, Kansas State University, Manhattan, Kansas, USA.
Srivatsan ParthasarathyDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Matthew M RamseyDepartment of Ophthalmology, Harvard Microbial Sciences Initiative, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
Matthew J GormanDivision of Biology, Kansas State University, Manhattan, Kansas, USA.
Theresa L BarkeDivision of Biology, Kansas State University, Manhattan, Kansas, USA.
Sriram VarahanDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Sally OlsonComparative Medicine Group, Kansas State University, Manhattan, Kansas, USA.
Michael S GilmoreDepartment of Ophthalmology, Harvard Microbial Sciences Initiative, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.
Zakria H AbdullahiDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Emmaleigh N HancockDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.
Lynn E HancockDepartment of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA lynnh@ku.edu.ORCID 0000-0003-3372-5406
University of Kansas · USKansas State University · USMassachusetts Eye and Ear Infirmary · US

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Douglas E Wright · 2012 to 2026
$63.0M
UNDERSTANDING THE ROLE OF SMALL RNAS IN ARABIDOPSIS POLLEN DEVELOPMENTP20RR016475 · NCRR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI LUSHINGTON, GERALD H · 2001 to 2011
$38.1M
The regulation of autolysis in Enterococcus faecalisR01AI077782 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI HANCOCK, LYNN E · 2010 to 2014
$1.4M
The role of peptide signaling in Enterococcus faecalis biofilm developmentR21AI117424 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI HANCOCK, LYNN E · 2017 to 2018
$407k
NCRR NIH HHS P20 RR016475NIAID NIH HHS R01 AI077782NIAID NIH HHS R21 AI117424NIGMS NIH HHS P20 GM103418
6 · The paper itself

Abstract

The alternative sigma factor σ

Indexed as

Gene ExpressionAnimalsBacterial ProteinsBiofilmsCarbonEnterococcus faecalisGene Expression Regulation, BacterialRabbitsSigma FactorVirulenceBacterial ProteinsCarbonSigma FactorCcpAendocarditisEnterococcus faecalismicroarraysRpoNUTI

Identifiers

PMID34006651
PMCPMC8262876
OpenAlexW3162830479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.