Evidence map›Paper›PMID 34006480›Full record

ArticleJournal of the American Pharmacists Association : JAPhA

Impact of a pilot community pharmacy system redesign on reducing over-the-counter medication misuse in older adults.

Aaron M Gilson, Jamie A Stone, Ashley O Morris, Roger L Brown, Ka Z Xiong, Nora Jacobson, Richard J Holden, Steven M Albert, Cynthia H Phelan, Denise L Walbrandt Pigarelli and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the American Pharmacists Association : JAPhA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Using a scenario-based hybrid approach to understand participant health behavior.Research in social & administrative pharmacy : RSAP · 2021
    Article
  7. Adapting a community pharmacy intervention to improve medication safety.Journal of the American Pharmacists Association : JAPhA
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Aaron M Gilson
Jamie A Stone
Ashley O Morris
Roger L Brown
Ka Z Xiong
Nora Jacobson
Richard J Holden
Steven M Albert
Cynthia H Phelan
Denise L Walbrandt Pigarelli
Robert M Breslow
Lauren Welch
Michelle A Chui

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
NRSA Training CoreTL1TR002375 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Vivek Prabhakaran · 2017 to 2026
$8.4M
Improving Over-the-Counter Medication Safety for Older AdultsR18HS024490 · AHRQ · UNIVERSITY OF WISCONSIN-MADISON · PI CHUI, MICHELLE ANNE · 2016 to 2018
$1.4M
AHRQ HHS R18 HS024490NCATS NIH HHS TL1 TR002375NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373
6 · The paper itself

Abstract

backgroundNo interventions have attempted to decrease misuse of over-the-counter (OTC) medications for adults aged 65 years or older (older adults) by addressing system barriers. An innovative structural pharmacy redesign (the Senior Section) was conceptualized to increase awareness of higher-risk OTC medications. The Senior Section contains a curated selection of OTC medications and is close to the prescription department to facilitate pharmacy staff-patient engagement to reduce misuse.

objectiveThis pilot study examined the Senior Section's effectiveness at influencing OTC medication misuse in older adults.

methodsA pretest-post-test nonequivalent groups design was used to recruit 87 older adults from 3 pharmacies. Using a hypothetical scenario, the participants selected an OTC medication that was compared with their medication list and health conditions, and their reported use was compared with the product labeling. Misuse outcomes comprised drug-drug, drug-disease, drug-age, and drug-label, with 5 subtypes. Patient characteristics were compiled into a propensity score matching logistic regression model to estimate their effects on the Senior Section's association with misuse at pre- or postimplementation.

resultsPatient characteristics were uniform between pre- and postimplementation, and, once entered into a propensity score matching model, drug-label misuse (exceeds daily dosage) statistically significantly lessened over time (z = -2.42, P = 0.015). In addition, the Senior Section reduced drug-label misuse (exceeds single dosage) for both the raw score model (z = -6.38, P = 0.011) and the model in which the patient characteristics propensity score was added (z = -5.82, P = 0.011). Despite these limited statistical effects, misuse was found to decrease after implementation for 7 of 11 comparisons.

conclusionThese nascent outcomes begin providing an evidence base to support a well-conceived, pharmacy-based OTC medication-aisle redesign for reducing older adult OTC medication misuse. The Senior Section, when broadly implemented, creates permanent structures and processes to assist older adults to access risk information when selecting safer OTC medications.

Indexed as

Community Pharmacy ServicesPharmaciesPrescription Drug MisuseAgedHumansNonprescription DrugsPilot ProjectsNonprescription Drugs

Identifiers

PMID34006480
PMCPMC8429243
OpenAlexW3153102118

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.