ArticleBMJ open2021
Association between preconception maternal stress and offspring birth weight: findings from an Australian longitudinal data linkage study.
Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention-deficit/hyperactivity disorder.The Journal of physiology · 2026Review
- Computational Approaches for Connecting Maternal Stress to Preterm Birth.Clinics in perinatology · 2024Review
- Patterns of Labour Interventions and Associated Maternal Biopsychosocial Factors in Australia: a Path Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- Canada's Colonial Genocide of Indigenous Peoples: A Review of the Psychosocial and Neurobiological Processes Linking Trauma and Intergenerational Outcomes.International journal of environmental research and public health · 2022Review
- Preconception stress exposure from childhood to adolescence and birth outcomes: The impact of stress type, severity and consistency.Frontiers in reproductive health · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveExamine the relationship between preconception stress and offspring birth weight.
settingPopulation-based cohort study linked with state-based administrative perinatal data.
participants6100 births from 3622 women from the 1973-1978 cohort of the Australian Longitudinal Study of Women's Health who (1) recorded a singleton birth between January 1997 and December 2011; (2) returned at least one follow-up survey within 3 years of conception; and (3) had complete data on perceived stress prior to conception. PRIMARY OUTCOME MEASURES: Linear generalised estimating equations were used to examine the relationship between preconception stress and a continuous measure of birth weight, exploring differences based on birth order and stress chronicity. The minimal sufficient adjustment set of covariates was determined by a directed acyclic graph.
resultsFor all births, there was no relationship between moderate/high acute or chronic stress and offspring birth weight in grams. Among first births only, there was a trend towards a relationship between moderate/high chronic stress and offspring birth weight. Offspring sex was associated with birth weight in all models, with female babies born lighter than male babies on average, after adjusting for covariates (p<0.0001).
conclusionsEffects of preconception stress on birth weight was largely driven by time to conception. With the timing of stress critical to its impact on obstetrical outcomes, preconception care should involve not only reproductive life planning but the space to provide interventions at critical periods so that optimal outcomes are achieved.
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