Evidence map›Paper›PMID 34004350›Full record

ArticleVision research2021

Antagonistic surround responses in different cones are mediated by feedback synapses from different horizontal cells.

Ai-Jun Zhang, Samuel M Wu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vision research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ai-Jun ZhangCullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, United States.
Samuel M WuCullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, United States. Electronic address: swu@bcm.edu.
Baylor College of Medicine · US

Funding

VISION RESEARCH CENTERP30EY002520 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$14.8M
PHYSIOLOGY AND PHARMACOLOGY OF SYNAPSES IN THE RETINAR01EY004446 · NEI · BAYLOR COLLEGE OF MEDICINE · PI WU, SAMUEL M · 1985 to 2014
$5.4M
ROD AND CONE SIGNALING PATHWAYS IN MAMMALIAN RETINAR01EY019908 · NEI · BAYLOR COLLEGE OF MEDICINE · PI WU, SAMUEL M · 2010 to 2020
$3.8M
NEI NIH HHS P30 EY002520NEI NIH HHS R01 EY004446NEI NIH HHS R01 EY019908
6 · The paper itself

Abstract

Cone photoreceptors are the first neurons along the visual pathway that exhibit center-surround antagonistic receptive fields, the basic building blocks for spatial information processing in the visual system. The surround responses in cones are mediated by the horizontal cells (HCs) via multiple feedback synaptic mechanisms. It has been controversial on which mechanisms are responsible for the surround-elicited depolarizing responses in cones (ΔV

Indexed as

Retinal Cone Photoreceptor CellsSynapsesFeedbackRetinaVisual PathwaysCenter-surround antagonistic receptive fieldDL-threo-β-Benzyloxyaspartic acidDouble conesGamma-aminobutyric acidGlutamate transporter associated chloride channelHorizontal cellsPicrotoxinSingle conesSurround-elicited depolarizing response in cones

Identifiers

PMID34004350
PMCPMC11210320
OpenAlexW3163225590

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.