Evidence map›Paper›PMID 34004214›Full record

ArticleUrology2021

Understanding the Health Characteristics and Treatment Choices of Older Men with Stress Urinary Incontinence.

Lindsay A Hampson, Anne M Suskind, Benjamin N Breyer, Lillian Lai, Matthew R Cooperberg, Rebecca L Sudore, Salomeh Keyhani, I Elaine Allen, Louise C Walter

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lindsay A HampsonDepartment of Urology, School of Medicine, University of California San Francisco, San Francisco, CA; Department of Surgery, San Francisco Veterans Affairs Medical Center, San Francisco, CA. Electronic address: Lindsay.hampson@ucsf.edu.
Anne M SuskindDepartment of Urology, School of Medicine, University of California San Francisco, San Francisco, CA.
Benjamin N BreyerDepartment of Urology, School of Medicine, University of California San Francisco, San Francisco, CA.
Lillian LaiDepartment of Urology, University of Michigan Medical School, Ann Arbor, MICH.
Matthew R CooperbergDepartment of Urology, School of Medicine, University of California San Francisco, San Francisco, CA; Department of Surgery, San Francisco Veterans Affairs Medical Center, San Francisco, CA.
Rebecca L SudoreDepartment of Medicine, School of Medicine, University of California San Francisco, San Francisco, CA; Department of Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, CA.
Salomeh KeyhaniDepartment of Medicine, School of Medicine, University of California San Francisco, San Francisco, CA; Department of Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, CA.
I Elaine AllenDepartment of Epidemiology & Biostatistics, School of Medicine, University of California San Francisco, San Francisco, CA.
Louise C WalterDepartment of Medicine, School of Medicine, University of California San Francisco, San Francisco, CA; Department of Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, CA.
University of California, San Francisco · USSan Francisco VA Medical Center · USUniversity of Michigan–Ann Arbor · US

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2013 to 2026
$19.9M
Mentoring Researchers in Advance Care Planning for Underrepresented Older Adults at Risk for Alzheimer’s Disease and Related Dementias and Their CaregiversK24AG054415 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REBECCA L SUDORE · 2017 to 2026
$1.7M
Understanding and Improving Treatment Decision-Making for Older Males with Stress Urinary IncontinenceR03AG064372 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HAMPSON, LINDSAY ANN · 2019 to 2020
$242k
NCATS NIH HHS UL1 TR001872NIA NIH HHS K24 AG054415NIA NIH HHS P30 AG044281NIA NIH HHS R03 AG064372
6 · The paper itself

Abstract

objectiveTo describe the health characteristics and current treatment choices of male stress urinary incontinence (mSUI) patients to inform patient-centered decision-making.

methodsWe identified a cohort of mSUI patients aged ≥65 at UCSF and San Francisco VA. Using retrospective chart review and telephone interviews, we ascertained demographics, incontinence characteristics, Charlson Comorbidity Index (score ≥ 4 indicates significant morbidity), frailty with Timed Up and Go (TUG) test, functional dependence with activities of daily living (ADL), calculated life expectancy, and assessed mental health and quality of life (QOL). Bivariate analysis evaluated associations between subject characteristics and ultimate treatment type (conservative vs surgery; sling vs sphincter). Logistic multivariable models evaluating treatment choice were also constructed.

resultsThe 130 participants had a mean age of 75 and a mean incontinence score of 14.2 representing moderately bothersome incontinence. Nearly 80% had significant morbidity, three-quarters had >50% 10-year mortality risk, 10% needed help with 1 + ADL and 22% had a TUG >10 seconds indicating frailty. The mean physical and mental QOL scores were similar to the general population. Anxiety and depression were reported by 3.9% and 10%. In univariate and multivariable analysis, only incontinence characteristics were associated with conservative vs surgical treatment choice (P < .01).

conclusionMulti-morbidity, functional dependence, frailty, and limited life expectancy are common among older men with mSUI, yet current treatment choices appear to be driven by incontinence characteristics. As such, mSUI surgery should be considered among men across the spectrum of health and life expectancy.

Indexed as

Patient PreferenceAgedHumansMaleRetrospective StudiesUrinary Incontinence, Stress

Identifiers

PMID34004214
PMCPMC9012599
OpenAlexW3160905885

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.