Evidence map›Paper›PMID 34004061›Full record

ArticleCancer communications (London, England)2021

Identification of immune-activating metabolite for enhancing T cell therapy of cancer.

Boyi Cong, Zenghui Cui, Xuetao Cao

Open access · goldAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer communications (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Transcriptional suppression of CD8Cancer communications (London, England) · 2021
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Boyi CongCollege of Life Sciences, Nankai University, Tianjin, 300071, P. R. China.
Zenghui CuiCollege of Life Sciences, Nankai University, Tianjin, 300071, P. R. China.
Xuetao CaoCollege of Life Sciences, Nankai University, Tianjin, 300071, P. R. China.ORCID 0000-0001-9677-7647
Nankai University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

National Natural Science Foundation of China 81788101
6 · The paper itself

Abstract

In this Research Highlight, we summarized the results from a study by Wu et al. published in Nature Cell Biology which uncovered that asparagine (Asn), a non-essential amino acid in mammalians, is able to enhance the TCR-mediated activation and efficacy of CD8

Indexed as

CD8-Positive T-LymphocytesNeoplasmsAnimalsCell- and Tissue-Based TherapyHumansLymphocyte Specific Protein Tyrosine Kinase p56(lck)PhosphorylationLymphocyte Specific Protein Tyrosine Kinase p56(lck)

Identifiers

PMID34004061
PMCPMC8286139
OpenAlexW3163463832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.