ArticleTranslational vision science & technology2021
Smart Eye Camera: A Validation Study for Evaluating the Tear Film Breakup Time in Human Subjects.
Article in Translational vision science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 29 citations in OpenAlex.
- Development of a Deep Learning Model to Estimate Anemia from Palpebral Conjunctiva Taken with a Portable Slit-Lamp Microscope.Bioengineering (Basel, Switzerland) · 2026Article
- The use of the smart eye camera for diagnosing and grading cataract in diabetic and non-diabetic patients in an outpatient setting in Jordan.International ophthalmology · 2026Article
- Devising a Coaching Method for a Smartphone-Based Slit-Lamp Microscope and Its Learning Effects: A Pilot Study.Journal of clinical medicine · 2026Article
- Smartphone-Based Portable Slit Lamp in Anterior Segment Diseases: A Narrative Review of Clinical Assessment and Integration with Artificial Intelligence.Ophthalmology and therapy · 2026Review
- Prospective Evaluation of Ocular Anterior Segment Morphology Changes in the Steep Trendelenburg Position During Robotic-Assisted Laparoscopic Prostatectomy.Journal of clinical medicine · 2026Article
- Telemedicine-based diagnosis and management of ocular chemical injury in a remote setting: A case report.Journal of general and family medicine · 2025Article
- Validation and optimization of smart eye camera as teleophthalmology device for the reduction of preventable and treatable blindness in Nigeria.Eye (London, England) · 2025Article
- Reliability and Accuracy of Smart Eye Camera in Determining Grading of Nuclear Cataract.Korean journal of ophthalmology : KJO · 2025Observational
- Article
- Clinical evaluation of corneal ulcer with a portable and smartphone-attachable slit lamp device: Smart Eye Camera.Scientific reports · 2025Article
- Evaluating the Effect of Image Enhancement on Diagnostic Reliability in Dry Eye Disease Using a Portable Imaging Device.Diagnostics (Basel, Switzerland) · 2024Article
- Primary Angle Closure Observed During a House Visit: A Case Treated With Laser Iridotomy.Cureus · 2024Article
- A Case of Traumatic Hyphema Diagnoses by Telemedicine Between a Remote Island and the Mainland of Tokyo.Cureus · 2024Article
- Development of the AI Pipeline for Corneal Opacity Detection.Bioengineering (Basel, Switzerland) · 2024Article
- Feasibility of Tear Meniscus Height Measurements Obtained with a Smartphone-Attachable Portable Device and Agreement of the Results with Standard Slit Lamp Examination.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- AI-based diagnosis of nuclear cataract from slit-lamp videos.Scientific reports · 2023Article
- Telemedicine for Cornea and External Disease: A Scoping Review of Imaging Devices.Ophthalmology and therapy · 2023Article
- Clinical observation of tear film breakup time with a novel smartphone-attachable technology.BMC ophthalmology · 2023Article
- Artificial intelligence to estimate the tear film breakup time and diagnose dry eye disease.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aimed to demonstrate the efficacy of a "Smart Eye Camera (SEC)" in comparison with the efficacy of the conventional slit-lamp microscope by evaluating their diagnostic functionality for dry eye disease (DED) in clinical cases. Methods: This retrospective study included 106 eyes from 53 adult Japanese patients who visited the Ophthalmology outpatient clinics in Keio University Hospital from June 2019 to March 2020. Tear film breakup time (TFBUT) and corneal fluorescence score (CFS) measurements for the diagnosis of DED were compared between the conventional slit-lamp microscope and SEC. Results: The objective findings of DED showed that there was a strong correlation between the conventional slit-lamp microscope and SEC with respect to TFBUT and CFS results (Spearman's r = 0.887, 95% confidence interval [CI] = 0.838-0.922, and r = 0.920, 95% CI = 0.884-0.945, respectively). The interobserver reliability between the conventional slit-lamp microscope and SEC showed a moderate agreement (weighted Kappa κ = 0.527, 95% CI = 0.517-0.537 and κ = 0.550, 95% CI = 0.539-0.561 for TFBUT and CFS, respectively). The diagnostic performance of the SEC for Asia Dry Eye Society diagnostic criteria showed a sensitivity of 0.957 (95% CI = 0.841-0.992), specificity of 0.900 (95% CI = 0.811-0.927), positive predictive value of 0.880 (95% CI = 0.774-0.912), and negative predictive value of 0.964 (95% CI = 0.869-0.993). Moreover, the area under the receiver operating characteristic curve was 0.928 (95% CI = 0.849-1.000). Conclusions: Compared with the conventional slit-lamp microscope, SEC has sufficient validity and reliability for diagnosing DED in the clinical setting. Translational Relevance: The SEC can portably evaluate TFBUT in both basic research and clinical care.
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