Evidence map›Paper›PMID 34003897›Full record

ArticleTranslational vision science & technology2021

Wide-Field Swept-Source Optical Coherence Tomography Angiography Analysis of the Periarterial Capillary-Free Zone in Branch Retinal Vein Occlusion.

Wenyi Tang, Jingli Guo, Xiaonan Zhuang, Ting Zhang, Ling Wang, Keyan Wang, Qing Chang, Wei Liu, Gezhi Xu

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Wenyi TangDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Jingli GuoDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Xiaonan ZhuangDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Ting ZhangDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Ling WangDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Keyan WangDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Qing ChangDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Wei LiuDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Gezhi XuDepartment of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Eye & ENT Hospital of Fudan University · CNFudan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the characteristics of the retinal periarterial capillary-free zone (paCFZ) with wide-field swept-source optical coherence tomography angiography (SS-OCTA) in eyes with branch retinal vein occlusion (BRVO). Methods: Seventy treatment-naïve eyes with BRVO and 35 healthy eyes were included. The paCFZ areas, artery calibers, and areas of the major arteries in the unaffected quadrants of BRVO eyes were measured in 12 × 12-mm SS-OCTA images and compared with those of the contralateral eyes and healthy eyes. Other multimodal imaging data were collected. Results: There were no significant differences in the unaffected artery caliber or area among the three groups (all P > 0.05). The unaffected paCFZ areas and the ratios of the unaffected paCFZ area to the counterpart artery area (paCFZ/artery area) of the major arteries were significantly larger than those in the contralateral or healthy eyes (all P < 0.05). Subgroup analysis revealed that the paCFZ/artery area value differed significantly between ischemic and nonischemic BRVO eyes (P < 0.01). The paCFZ/artery area value was positively correlated with logMAR best-corrected visual acuity, symptom duration, central macular thickness, and retinal nonperfusion area in BRVO. Conclusions: Quantitative SS-OCTA measurements confirmed enlarged paCFZs along the unaffected major retinal arteries in BRVO eyes. The paCFZ parameters were correlated with symptom duration, retinal ischemia, and visual function. Translational Relevance: Retinal periarterial capillary-free zones in BRVO can be non-invasively measured by SS-OCTA, assisting in clinically identifying retinal ischemia and evaluating visual function.

Indexed as

Retinal Vein OcclusionFluorescein AngiographyHumansRetinal VesselsRetrospective StudiesTomography, Optical CoherenceVisual Acuity

Identifiers

PMID34003897
PMCPMC7881276
OpenAlexW3126658604

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.