Evidence map›Paper›PMID 34003883›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2021

Association of Hearing Impairment With Higher-Level Physical Functioning and Walking Endurance: Results From the Baltimore Longitudinal Study of Aging.

Pablo Martinez-Amezcua, Pei-Lun Kuo, Nicholas S Reed, Eleanor M Simonsick, Yuri Agrawal, Frank R Lin, Jennifer A Deal, Luigi Ferrucci, Jennifer A Schrack

Open access · greenAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  8. Review
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  12. The Relationship between Chronic Unilateral Hearing Loss, Balance Function, and Falls Is Not Informed by Vestibular Status.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2025
    Article
  13. Review
  14. Depression and Health-Related Quality of Life Among Older Adults With Hearing Loss in the ACHIEVE Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024
    Article
  15. Article
  16. Article
  17. Hearing Loss and Physical Activity Among Older Adults in the United States.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  18. Article
  19. Article
  20. Hearing Loss and Frailty among Older Adults: The Atherosclerosis Risk in Communities Study.Journal of the American Medical Directors Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pablo Martinez-AmezcuaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0002-3076-0946
Pei-Lun KuoIntramural Research Program, National Institute on Aging, Baltimore, Maryland, USA.
Nicholas S ReedDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Eleanor M SimonsickIntramural Research Program, National Institute on Aging, Baltimore, Maryland, USA.
Yuri AgrawalDepartment of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Frank R LinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Jennifer A DealDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Luigi FerrucciIntramural Research Program, National Institute on Aging, Baltimore, Maryland, USA.ORCID 0000-0002-6273-1613
Jennifer A SchrackDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.ORCID 0000-0001-9244-9267
Johns Hopkins University · USNational Institute on Aging · US

Funding

The Baltimore Longitudinal Study Of AgingZIAAG000015 · NIA · NATIONAL INSTITUTE ON AGING · PI SIMONSICK, ELEANOR MARIE · 2009 to 2025
$116.9M
Contribution of sensorimotor function to risk and pathogenic mechanisms of Alzheimer's disease and related dementiasR01AG061786 · NIA · JOHNS HOPKINS UNIVERSITY · PI AGRAWAL, YURI, LIN, FRANK R · 2019 to 2023
$3.7M
The Role of Hearing Loss in Health Care Outcomes.K23AG065443 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REED, NICHOLAS SALVATORE · 2020 to 2024
$943k
Role and Mechanism of Hearing Impairment in Cognitive Decline and DementiaK01AG054693 · NIA · JOHNS HOPKINS UNIVERSITY · PI DEAL, JENNIFER ANNE · 2017 to 2022
$773k
Intramural NIH HHSNIA NIH HHS K01 AG054693NIA NIH HHS K23AG065443NIA NIH HHS R01 AG061786
6 · The paper itself

Abstract

backgroundAlthough hearing impairment (HI) is linked to poorer physical functioning, the longitudinal associations between HI and higher-level functional measures are unclear.

methodData are from the Baltimore Longitudinal Study of Aging (2012-2019). Using pure-tone audiometry, we categorized hearing into normal, mild, and moderate or greater HI. Physical function was assessed with the expanded Short Physical Performance Battery (eSPPB) and walking endurance with time to walk 400 m. Multivariable and mixed-effects linear models tested the hypotheses that participants with HI, at baseline, have poorer physical performance and walking endurance, and faster decline over time (up to 6 measurements). In a subset (n = 526), we further adjusted for vestibular function. Among participants with HI, we evaluated the differences in eSPPB scores and walking endurance between hearing aid users and nonusers.

resultsOf 831 participants, 26% had mild, and 17% moderate or greater HI. After adjustment for demographics and medical history, moderate or greater impairment versus normal hearing was associated with poorer function (0.17 [95% CI: 0.09, 0.26] lower eSPPB score, and 13.3 [95% CI: 3.31, 23.4] seconds slower 400-m walk time) and faster decline in these parameters over 6 years. Adjustment for vestibular function did not attenuate these associations. Hearing aid users walked 400 m 24 seconds faster than nonusers (p = .001).

conclusionModerate or greater HI is associated with poorer initial and greater decline in higher-level physical performance. The observation that hearing aid users had better walking endurance suggests that screening for and treatment of HI may delay or slow progression of hearing-related functional decline.

Indexed as

Hearing LossWalkingAgingBaltimoreHumansLongitudinal StudiesFitnessHearing lossPhysical function

Identifiers

PMID34003883
PMCPMC8436975
OpenAlexW3163833008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.