Evidence map›Paper›PMID 34003748›Full record

ArticleIEEE transactions on ultrasonics, ferroelectrics, and frequency control2021

Real-Time In Vivo Imaging of Human Liver Vasculature Using Coherent Flow Power Doppler: A Pilot Clinical Study.

You Leo Li, Dongwoon Hyun, Jessica Ducey-Wysling, Isabelle Durot, Aurelie D'Hondt, Bhavik Natvar Patel, Jeremy J Dahl

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

You Leo Li
Dongwoon Hyun
Jessica Ducey-Wysling
Isabelle Durot
Aurelie D'Hondt
Bhavik Natvar Patel
Jeremy J Dahl
Stanford University · USCentre Hospitalier Interrégional Edith Cavell · BEMayo Clinic in Arizona · USRegionalspital Emmental · CHStanford Health Care · US

Funding

Clutter Suppression in Echocardiography Using Short-Lag Spatial Coherence ImagingR01EB013661 · NIBIB · STANFORD UNIVERSITY · PI DAHL, JEREMY · 2012 to 2021
$3.1M
High Sensitivity Flow Imaging of the Human Placenta with Coherence-Based Doppler UltrasoundR01HD086252 · NICHD · STANFORD UNIVERSITY · PI DAHL, JEREMY · 2015 to 2019
$2.4M
A 1.5-T superconducting solenoid-dipole magnet for a magic-angle spinning fieldR01EB013231 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI IWASA, YUKIKAZU · 2011 to 2013
$1.9M
NIBIB NIH HHS R01 EB013231NIBIB NIH HHS R01 EB013661NICHD NIH HHS R01 HD086252
6 · The paper itself

Abstract

Power Doppler (PD) is a commonly used technique for flow detection and vessel visualization in radiology clinics. Despite its broad set of applications, PD suffers from multiple noise sources and artifacts, such as thermal noise, clutter, and flash artifacts. In addition, a tradeoff exists between acquisition time and Doppler image quality. These limit the ability of clinical PD imaging in deep-lying and small-vessel detection and visualization, particularly among patients with high body mass indices (BMIs). To improve the Doppler vessel detection, we have previously proposed coherent flow PD (CFPD) imaging and demonstrated its performance on porcine vasculature. In this article, we report on a pilot clinical study of CFPD imaging on healthy human volunteers and patients with high BMI to assess the clinical feasibility of the technique in liver imaging. In this study, we built a real-time CFPD imaging system using a graphical processing unit (GPU)-based software beamformer and a CFPD processing module. Using the real-time CFPD imaging system, the liver vasculature of 15 healthy volunteers with normal BMI below 25 and 15 patients with BMI greater than 25 was imaged. Both PD and CFPD image streams were produced simultaneously. The generalized contrast-to-noise ratio (gCNR) of the PD and CFPD images was measured to provide the quantitative evaluation of image quality and vessel detectability. Comparison of PD and CFPD image shows that gCNR is improved by 35% in healthy volunteers and 28% in high BMI patients with CFPD compared to PD. Example images are provided to show that the improvement in the Doppler image gCNR leads to greater detection of small vessels in the liver. In addition, we show that CFPD can suppress in vivo reverberation clutter in clinical imaging.

Indexed as

LiverUltrasonography, DopplerAnimalsArtifactsHumansPilot ProjectsSignal-To-Noise RatioSwine

Identifiers

PMID34003748
PMCPMC8515835
OpenAlexW3162245076

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.