Evidence map›Paper›PMID 34003685›Full record

Trial reportCirculation. Cardiovascular quality and outcomes2021

Changes in Home Blood Pressure Monitored Among Elderly Patients With Hypertension During the COVID-19 Outbreak: A Longitudinal Study in China Leveraging a Smartphone-Based Application.

Shuyuan Zhang, Xiaoyang Zhou, Youren Chen, Lixin Wang, Bingpo Zhu, Yinong Jiang, Peili Bu, Wei Liu, Dianfang Li, Yuming Li and 12 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Circulation. Cardiovascular quality and outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03015311 (Strategy of Systolic Blood Pressure Intervention in the Elderly Hypertensive Patients), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03015311 naunknown statusnot on this map

Strategy of Systolic Blood Pressure Intervention in the Elderly Hypertensive Patients: A Prospective Randomized Open-Label Blinded-Endpoint Trial

TypeinterventionalSponsorChinese Academy of Medical Sciences, Fuwai HospitalRan2017 to 2021Enrolled8,000ConditionsPrimary HypertensionArmsIntensive BP control, Standard BP control
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 18 institutions in 1 country.

Shuyuan Zhang *State Key Laboratory of Cardiovascular Disease, Hypertension Center, FuWai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China (S.Z., J.B., W.Z., J.C.).
Xiaoyang Zhou *Renmin Hospital of Wuhan University, Hubei, China (X.Z.).
Youren Chen *The Second Affiliated Hospital to Medical College Shantou University, Guangdong, China (Y.C.).
Lixin WangThe First Affiliated Hospital of Hebei North University, Zhangjiakou, China (L.W.).
Bingpo ZhuKang Ya Hospital, Yiyang, Hunan, China (B.Z.).
Yinong JiangThe 1st Affiliated Hospital of Dalian Medical University, Liaoning, China (Y.J.).
Peili BuQilu Hospital of Shandong University, Jinan, China (P.B.).
Wei LiuBeijing Hospital, China (W.L.).
Dianfang LiHongxinglong Center Hospital, Shuangyashan, Heilongjiang, China (D.L.).
Yuming LiPingjin Hospital, Logistics University of PAPF, Tianjin, China (Yuming Li).
Yanhua TaoNanchang Sixth Hospital, Jiangxi, China (Y.T.).
Jie RenShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Taiyuan, China (J.R.).
Li FuBenxi Railway Hospital, Liaoning, China (L.F.).
Yufeng LiBeijing Pinggu Hospital, China (Yufeng Li).
Xiaomei ShenFirst Hospital of Shanxi Medical University, Taiyuan, China (X.S.).
Hualing LiuZhoukou City Central Hospital, Henan, China (H.L.).
Gang SunThe Second Affiliated Hospital of Baotou Medical College, Inner Mongolia, China (G.S.).
Xinjuan XuFirst Affiliated Hospital of Xinjiang Medical University, Urumqi, China (X.X.).
Jingjing BaiState Key Laboratory of Cardiovascular Disease, Hypertension Center, FuWai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China (S.Z., J.B., W.Z., J.C.).
Weili ZhangState Key Laboratory of Cardiovascular Disease, Hypertension Center, FuWai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China (S.Z., J.B., W.Z., J.C.).
Jun CaiState Key Laboratory of Cardiovascular Disease, Hypertension Center, FuWai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China (S.Z., J.B., W.Z., J.C.).
STEP Study Group
Chinese Academy of Medical Sciences & Peking Union Medical College · CN302 Military Hospital of China · CN82th Hospital of Pla · CNBeijing Anding Hospital · CNBeijing Hospital · CNChina Railway Corporation · CNDalian Medical University · CNHebei North University · CNHeilongjiang Provincial Hospital · CNQilu Hospital of Shandong University · CNSecond Affiliated Hospital of Inner Mongolia Medical University · CNShantou University · CNShanxi Academy of Medical Sciences · CNShanxi Medical University · CNSouthern University of Science and Technology · CNWuhan University · CNXinjiang Medical University · CNZhoukou City Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe coronavirus disease 2019 (COVID-19) pandemic has impacted clinical care worldwide. Evidence of how this health crisis affected common conditions like blood pressure (BP) control is uncertain.

methodsWe used longitudinal BP data from an ongoing randomized clinical trial to examine variations in home BP monitored via a smartphone-based application (app) in a total of 7394 elderly patients with hypertension aged 60 to 80 years stratified by their location in Wuhan (n=283) compared with other provinces of China (n=7111). Change in morning systolic BP (SBP) was analyzed for 5 30-day phases during the pandemic, including preepidemic (October 21 to November 20, 2019), incubation (November 21 to December 20, 2019), developing (December 21, 2019 to January 20, 2020), outbreak (January 21 to February 20, 2020), and plateau (February 21 to March 21, 2020).

resultsCompared with non-Wuhan areas of China, average morning SBP (adjusted for age, sex, body mass index) in Wuhan patients was significantly higher during the epidemic growth phases, which returned to normal at the plateau. Between-group differences in ΔSBP were +2.5, +3.0, and +2.1 mm Hg at the incubation, developing, and outbreak phases of COVID-19 (

conclusionsOur data demonstrate that the COVID-19 pandemic was associated with a short-term increase in morning SBP among elderly patients with hypertension in Wuhan but not other parts of China. Further study will be needed to understand if these findings extended to other parts of the world substantially affected by the virus. Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT03015311.

Indexed as

Blood Pressure DeterminationSmartphoneAgedAged, 80 and overAntihypertensive AgentsChinaCOVID-19FemaleHumansHypertensionLongitudinal StudiesMaleMiddle AgedSelf CareAntihypertensive Agentscoronavirus disease 2019home blood pressurehypertensionpandemicsmartphone-based application

Identifiers

PMID34003685
PMCPMC8136456
OpenAlexW3163431466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.