Evidence map›Paper›PMID 34003586›Full record

ArticlePharmacology research & perspectives2021

Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium-dependent, non-D

Jillian S Weissenrieder, Jessie L Reed, George-Lucian Moldovan, Martin T Johnson, Mohamed Trebak, Jeffrey D Neighbors, Richard B Mailman, Raymond J Hohl

Open access · goldAbstract read
In one paragraph

Article in Pharmacology research & perspectives, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jillian S WeissenriederDepartment of Medicine, Penn State College of Medicine, Hershey, PA, USA.
Jessie L ReedDepartment of Medicine, Penn State College of Medicine, Hershey, PA, USA.
George-Lucian MoldovanPenn State Cancer Institute, Hershey, PA, USA.
Martin T JohnsonPenn State Cancer Institute, Hershey, PA, USA.
Mohamed TrebakPenn State Cancer Institute, Hershey, PA, USA.
Jeffrey D NeighborsDepartment of Medicine, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0002-0698-4181
Richard B MailmanDepartment of Pharmacology, Penn State College of Medicine, Hershey, PA, USA.
Raymond J HohlDepartment of Medicine, Penn State College of Medicine, Hershey, PA, USA.
Penn State Milton S. Hershey Medical Center · US

Funding

Ca2+ Signaling Networks in Health and DiseaseR35HL150778 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TREBAK, MOHAMED · 2020 to 2025
$5.4M
VIRUSES AND CANCERT32CA060395 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MEYERS, CRAIG M · 1994 to 2021
$4.3M
The Mitochondrial Sodium/Calcium Exchanger (NCLX) in Airway Smooth Muscle Remodeling during AsthmaF30HL147489 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI JOHNSON, MARTIN T · 2019 to 2022
$149k
NCI NIH HHS T32 CA060395NHLBI NIH HHS F30 HL147489NHLBI NIH HHS R35 HL150778
6 · The paper itself

Abstract

Dopamine D

Indexed as

Antipsychotic AgentsCalcium SignalingCell Line, TumorCell SurvivalCentral Nervous System NeoplasmsDopamine AgonistsDopamine D2 Receptor AntagonistsGlioblastomaHumansReceptors, Dopamine D2Antipsychotic AgentsDopamine AgonistsDopamine D2 Receptor AntagonistsReceptors, Dopamine D2antipsychoticcalcium signalingdopamineglioblastoma

Identifiers

PMID34003586
PMCPMC8130568
OpenAlexW3162607162

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.