Evidence map›Paper›PMID 34003427›Full record

ArticleJournal of general internal medicine2021

Racial and Ethnic Disparities in Hospital Admissions from COVID-19: Determining the Impact of Neighborhood Deprivation and Primary Language.

Nicholas E Ingraham, Laura N Purcell, Basil S Karam, R Adams Dudley, Michael G Usher, Christopher A Warlick, Michele L Allen, Genevieve B Melton, Anthony Charles, Christopher J Tignanelli

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Nicholas E Ingraham *Department of Medicine, Division of Pulmonary and Critical Care, University of Minnesota, Minneapolis, MN, USA. ingra107@umn.edu.ORCID 0000-0002-0292-0594
Laura N Purcell *Department of Surgery, University of North Carolina, Chapel Hill, NC, USA.
Basil S KaramDepartment of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
R Adams DudleyDepartment of Medicine, Division of Pulmonary and Critical Care, University of Minnesota, Minneapolis, MN, USA.
Michael G UsherDepartment of Medicine, Division of General Internal Medicine, University of Minnesota, Minneapolis, MN, USA.
Christopher A WarlickDepartment of Urology, University of Minnesota, Minneapolis, MN, USA.
Michele L AllenDepartment of Family Medicine and Community Health, University of Minnesota, Minneapolis, MN, USA.
Genevieve B MeltonInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
Anthony Charles *Department of Surgery, University of North Carolina, Chapel Hill, NC, USA.
Christopher J Tignanelli *Institute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
TRAINING-PULMONARY CELL &MOLECULAR BIOLOGY &PHYSIOLOGYT32HL007741 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DUDLEY, R. ADAMS, INGBAR, DAVID H · 1994 to 2023
$13.9M
Institutional Career Development CoreKL2TR002492 · NCATS · UNIVERSITY OF MINNESOTA · PI INGBAR, DAVID H · 2018 to 2022
$6.3M
Minnesota Learning Health System Mentored Career Development Program (MN-LHS)K12HS026379 · AHRQ · UNIVERSITY OF MINNESOTA · PI BEEBE, TIMOTHY, LINZER, MARK · 2018 to 2022
$2.9M
Health Information Exchange Utilization and Inter-hospital Transfer OutcomesR01HS026732 · AHRQ · UNIVERSITY OF MINNESOTA · PI USHER, MICHAEL G. · 2019 to 2022
$1.3M
Agency for Healthcare Research and Quality K12HS026379Agency for Healthcare Research and Quality R01HS24532Agency for Healthcare Research and Quality R01HS26732AHRQ HHS K12 HS026379AHRQ HHS R01 HS026732NCATS NIH HHS KL2 TR002492NCATS NIH HHS KL2TR002492NCATS NIH HHS UL1TR002494NHLBI NIH HHS T32 HL007741NHLBI NIH HHS T32HL07741
6 · The paper itself

Abstract

backgroundDespite past and ongoing efforts to achieve health equity in the USA, racial and ethnic disparities persist and appear to be exacerbated by COVID-19.

objectiveEvaluate neighborhood-level deprivation and English language proficiency effect on disproportionate outcomes seen in racial and ethnic minorities diagnosed with COVID-19.

designRetrospective cohort study

settingHealth records of 12 Midwest hospitals and 60 clinics in Minnesota between March 4, 2020, and August 19, 2020 PATIENTS: Polymerase chain reaction-positive COVID-19 patients EXPOSURES: Area Deprivation Index (ADI) and primary language MAIN MEASURES: The primary outcome was COVID-19 severity, using hospitalization within 45 days of diagnosis as a marker of severity. Logistic and competing-risk regression models assessed the effects of neighborhood-level deprivation (using the ADI) and primary language. Within race, effects of ADI and primary language were measured using logistic regression.

resultsA total of 5577 individuals infected with SARS-CoV-2 were included; 866 (n = 15.5%) were hospitalized within 45 days of diagnosis. Hospitalized patients were older (60.9 vs. 40.4 years, p < 0.001) and more likely to be male (n = 425 [49.1%] vs. 2049 [43.5%], p = 0.002). Of those requiring hospitalization, 43.9% (n = 381), 19.9% (n = 172), 18.6% (n = 161), and 11.8% (n = 102) were White, Black, Asian, and Hispanic, respectively. Independent of ADI, minority race/ethnicity was associated with COVID-19 severity: Hispanic patients (OR 3.8, 95% CI 2.72-5.30), Asians (OR 2.39, 95% CI 1.74-3.29), and Blacks (OR 1.50, 95% CI 1.15-1.94). ADI was not associated with hospitalization. Non-English-speaking (OR 1.91, 95% CI 1.51-2.43) significantly increased odds of hospital admission across and within minority groups.

conclusionsMinority populations have increased odds of severe COVID-19 independent of neighborhood deprivation, a commonly suspected driver of disparate outcomes. Non-English-speaking accounts for differences across and within minority populations. These results support the ongoing need to determine the mechanisms that contribute to disparities during COVID-19 while also highlighting the underappreciated role primary language plays in COVID-19 severity among minority groups.

Indexed as

COVID-19EthnicityFemaleHospitalizationHospitalsHumansLanguageMaleRetrospective StudiesSARS-CoV-2

Identifiers

PMID34003427
PMCPMC8130213

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.