ArticleJournal of cancer research and clinical oncology2021
The log odds of negative lymph nodes/T stage: a new prognostic and predictive tool for resected gastric cancer patients.
Article in Journal of cancer research and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Log odds of negative lymph nodes/T stage as a novel predictor of post-resection outcome in non-small cell lung cancer patients.Discover oncology · 2025Article
- Prognostic model for log odds of negative lymph node in locally advanced rectal cancer via interpretable machine learning.Scientific reports · 2025Article
- Development and validation of a Log odds of negative lymph nodes/T stage ratio-based prognostic model for gastric cancer.Frontiers in oncology · 2025Article
- Prognostic value of the log odds of negative lymph nodes/T stage ratio (LONT) in postoperative esophageal cancer: a SEER-based study.Frontiers in oncology · 2025Article
- Predictive value of current nodal staging systems and development of machine learning nomogram for resectable pancreatic head cancer: a population-based study and multicenter validation.Frontiers in immunology · 2025Article
- Article
- Machine learning methods predict recurrence of pN3b gastric cancer after radical resection.Translational cancer research · 2024Article
- Recursive partitioning staging system based on the log odds of the negative lymph node/T stage ratio in colon mucinous adenocarcinoma.Frontiers in immunology · 2024Article
- Development of a well-defined tool to predict the overall survival in lung cancer patients: an African based cohort.BMC cancer · 2023Article
- Article
- Efficacy of Lymph Node Location-Number Hybrid Staging System on the Prognosis of Gastric Cancer Patients.Cancers · 2023Article
- Development and validation of a clinical cure marker based on negative lymph nodes for gastric cancer after gastrectomy.Frontiers in surgery · 2023Article
- Log odds of negative lymph nodes/T stage ratio (LONT): A new prognostic tool for differentiated thyroid cancer without metastases in patients aged 55 and older.Frontiers in endocrinology · 2023Article
- Gastric cancer clinical characteristics and their altered trends in South China: An epidemiological study with 2,800 cases spanning 26 years.Frontiers in oncology · 2023Article
- Predictive Value of the Log Odds of Negative Lymph Nodes/T Stage as a Novel Prognostic Factor in Bladder Cancer Patients After Radical Cystectomy.Frontiers in oncology · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
purposeWhen only the TNM classification is used to predict survival in gastric cancer (GC) patients, the impact of the degree of lymphadenectomy on the prognosis is neglected. This study aimed to establish a more effective nomogram based on the log odds of negative lymph nodes/T stage ratio (LONT) to predict survival in surgically treated GC patients.
methodsThe data of resected GC patients were extracted from the Surveillance, Epidemiology, and End Results Program (SEER) database. Univariate and multivariate Cox regression analyses were used to identify the significant prognostic factors. The prognostic performance was assessed using a calibration plot, concordance index (C-index), and area under the (time-dependent receiver operating characteristic) curve (AUC) to compare the predicted survival probability based on the nomogram score groups.
resultsThe results showed LONT as an independent prognostic factor for cancer-specific survival (CSS) and overall survival (OS), independent of clinicopathological factors. After removing potential redundancy, only LONT, T stage, N stage, location and age were used in the final nomogram model. The model had a higher C-index (0.736 ± 0.012) and AUC (0.798) than the TNM staging system (0.685 ± 0.012 and 0.744). The nomogram score could predict a significant survival difference between any two adjacent groups in terms of CSS and OS.
conclusionHigh LONT is associated with improved survival of gastric cancer patients, independent of other clinicopathological factors. The prognostic nomogram model based on LONT could effectively predict CSS and OS for resectable GC patients.
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