Evidence map›Paper›PMID 34003247›Full record

ArticleDatabase : the journal of biological databases and curation2021

An overview of graph databases and their applications in the biomedical domain.

Santiago Timón-Reina, Mariano Rincón, Rafael Martínez-Tomás

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. PheBee: A Graph-Aware System for Scalable, Traceable, and Semantic Phenotyping.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Review
  5. Article
  6. The TOXIN knowledge graph: supporting animal-free risk assessment of cosmetics.Database : the journal of biological databases and curation · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. FGDB: a comprehensive graph database of ligand fragments from the Protein Data Bank.Database : the journal of biological databases and curation · 2022
    Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Santiago Timón-ReinaDepartamento de Inteligencia Artificial, Universidad Nacional de Educación a Distancia (UNED), C/Juan del Rosal, 16 Ciudad Universitaria, Madrid 28040, Spain.
Mariano RincónDepartamento de Inteligencia Artificial, Universidad Nacional de Educación a Distancia (UNED), C/Juan del Rosal, 16 Ciudad Universitaria, Madrid 28040, Spain.
Rafael Martínez-TomásDepartamento de Inteligencia Artificial, Universidad Nacional de Educación a Distancia (UNED), C/Juan del Rosal, 16 Ciudad Universitaria, Madrid 28040, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past couple of decades, the explosion of densely interconnected data has stimulated the research, development and adoption of graph database technologies. From early graph models to more recent native graph databases, the landscape of implementations has evolved to cover enterprise-ready requirements. Because of the interconnected nature of its data, the biomedical domain has been one of the early adopters of graph databases, enabling more natural representation models and better data integration workflows, exploration and analysis facilities. In this work, we survey the literature to explore the evolution, performance and how the most recent graph database solutions are applied in the biomedical domain, compiling a great variety of use cases. With this evidence, we conclude that the available graph database management systems are fit to support data-intensive, integrative applications, targeted at both basic research and exploratory tasks closer to the clinic.

Indexed as

Database Management SystemsDatabases, Factual

Identifiers

PMID34003247
PMCPMC8130509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.