Evidence map›Paper›PMID 34002931›Full record

ArticleCancer medicine2021

The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study.

Mimi Zhai, Dan Zhang, Jianhai Long, Yi Gong, Fei Ye, Sushun Liu, Yamin Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 4 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 73 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mimi ZhaiXiangya Nursing School, Central South University, Changsha, Hunan, China.ORCID 0000-0001-8622-757X
Dan ZhangClinical Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Jianhai LongDepartment of Respiratory, Beijing Tiantan Hospital, Capital Medicine University, Beijing, China.
Yi GongDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Fei YeDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Sushun LiuDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yamin LiClinical Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Central South University · CNBeijing Tian Tan Hospital · CN

Funding

Chen Xiaoping Science and Technology Development Foundation CXPJJH11900001-2019334Hunan Provincial Natural Science Foundation of China 2018JJ3715
6 · The paper itself

Abstract

backgroundThyroid cancer is a growing threat to human health. Few studies have explored trends of thyroid cancer and relationships with social development factors. In this study, we explored the trend and relationship based on GBD.

methodsBy using GBD study, we obtained detailed data of thyroid cancer. Incidence, mortality and DALY were used to assess epidemiological characteristics. ASR and EAPC were used to estimate the trend.

resultsGlobally, the incidence significantly increased from 1990 to 2017, especially in high-income regions. Males and middle SDI region demonstrated a higher increase of age-standardized incidence rates. Unlike incidence trend, mortality trend showed a minor increase, and even showed a decreasing trend in some regions such as Eastern Sub-Saharan Africa. Additionally, the DALY trend also demonstrated a slightly increase with an EAPC of 0.77 (95% CI 0.73-0.81). More significant increase of DALY was found in males, middle SDI region and high-income Asia Pacific. The incidence of thyroid cancer peaked in middle-aged people, while the mortality and DALY peaked in elder-aged. Moreover, the proportion of thyroid cancer deaths contributable to high BMI was highest in developed countries and middle-aged people.

conclusionsThyroid cancer is a public health problem worldwide. Over-diagnosis might be partly responsible for its rising trend. It remains us to revise the guidelines to avoid unnecessary burdens. Moreover, we should pay attention to the risk factors of thyroid cancer. More targeted measures should be formulated to improve potential environmental and lifestyle-related factors which might contribute to rising trend of thyroid cancer.

Indexed as

Global Burden of DiseaseAdultAgedAged, 80 and overAge DistributionAge FactorsBody Mass IndexDeveloped CountriesDeveloping CountriesDisability-Adjusted Life YearsEpidemiologyFemaleGlobal HealthHumansIncidenceMaleASREAPCGBD studyrisk factorthyroid cancer

Identifiers

PMID34002931
PMCPMC8267141
OpenAlexW3163714129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.