ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2022
Social network characteristics moderate associations between cortical thickness and cognitive functioning in older adults.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- The Association Between Social Isolation, Functional Social Support, and Memory: A Mediation Analysis of the Canadian Longitudinal Study on Aging.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026Article
- Structural social factors modify the association between Alzheimer's pathology and cognitive function.The journal of prevention of Alzheimer's disease · 2026Observational
- Brain and cognitive correlates of social status across race/ethnicity and sex/gender.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Family availability and memory function and decline among adults aged ≥51 in England and the United States, 2004-2019.SSM - population health · 2025Article
- Effects of self-managed lifestyle behavioral changes on cognitive impairment control in Chinese older adults: a population-based prospective study.Translational psychiatry · 2025Article
- Marital status, brain health, and cognitive reserve among diverse older adults.Journal of the International Neuropsychological Society : JINS · 2025Article
- Loneliness, cerebrovascular and Alzheimer's disease pathology, and cognition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Higher Number of Children Is Associated With Increased Risk of Generalization Deficits in Older African American Women.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Salience Network Functional Connectivity Mediates Association Between Social Engagement and Cognition in Non-Demented Older Adults: Exploratory Investigation.Journal of Alzheimer's disease reports · 2024Article
- Association between loneliness and cognitive function, and brain volume in community-dwelling elderly.Frontiers in aging neuroscience · 2024Article
- Investigating Biological Pathways Underpinning the Longitudinal Association Between Loneliness and Cognitive Impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Why the cognitive "fountain of youth" may be upstream: Pathways to dementia risk and resilience through social connectedness.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- Psychosocial Protective Factors in Cognitive Aging: A Targeted Review.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2021Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
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Abstract
introductionPrior research suggests that the strength of association between Alzheimer's disease (AD) pathology and lower cognitive performance is influenced by modifiable psychosocial factors, such as social network size. However, little is known about distinct social relationship types.
methodsThe current cross-sectional study used data from the Washington Heights-Inwood Columbia Aging Project to examine whether social network characteristics (i.e., total size, spouse/partner, number of children, other relatives, friends) moderate associations between cortical thickness in regions implicated in AD and cognitive performance.
resultsLower cortical thickness was associated with worse global cognition among individuals with smaller friend networks, but not among individuals with larger friend networks. This pattern of results was most prominent for language and speed/executive functioning. DISCUSSION: Longitudinal and intervention studies are needed to determine whether these cross-sectional findings reflect a protective effect of later-life friendships for maintaining cognitive performance in the context of poorer brain health.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.