Evidence map›Paper›PMID 34002634›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study.

Joel D Trinity, Jesse C Craig, Caitlin C Fermoyle, Alec I McKenzie, Matthew T Lewis, Soung Hun Park, Matthew T Rondina, Russell S Richardson

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. The impact of age and exercise training on endothelial-mediated mechanisms of vasodilation during passive leg movement in males.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Effect of physical activity on long COVID fatigue: an unsolved enigma.European journal of translational myology · 2023
    Article
  8. Musculoskeletal involvement: COVID-19 and post COVID 19.Turkish journal of physical medicine and rehabilitation · 2023
    Review
  9. Article
  10. Article
  11. COVID-19 controls causing a kerfuffle.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
    Article
  12. Article
  13. Resistance Training before, during, and after COVID-19 Infection: What Have We Learned So Far?International journal of environmental research and public health · 2022
    Review
  14. Review
  15. Observational
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joel D TrinityGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.
Jesse C CraigGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.ORCID 0000-0001-5959-4139
Caitlin C FermoyleGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.ORCID 0000-0003-1027-7081
Alec I McKenzieGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.ORCID 0000-0002-6336-8684
Matthew T LewisGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.ORCID 0000-0003-0580-6866
Soung Hun ParkGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.
Matthew T RondinaGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.
Russell S RichardsonGeriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah.
University of Utah · US

Funding

TRAINING IN CARDIOVASCULAR RESEARCHT32HL007576 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Stavros George Drakos, Robin M Shaw · 1985 to 2026
$10.6M
Translational Control of Megakaryocyte and Platelet Gene Expression in DiseaseR35HL145237 · NHLBI · UNIVERSITY OF UTAH · PI WEYRICH, ANDREW S · 2019 to 2025
$4.7M
Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction during DisuseR01HL142603 · NHLBI · UNIVERSITY OF UTAH · PI TRINITY, JOEL DOUGLAS · 2019 to 2023
$2.9M
Translational Control of Megakaryocyte and Platelet Function in SepsisR01HL142804 · NHLBI · UNIVERSITY OF UTAH · PI RONDINA, MATTHEW THOMAS · 2018 to 2021
$1.9M
Platelet Reprogramming During InflammationI01CX001696 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI Matthew Thomas Rondina · 2018 to 2026
–
CSRD VA I01 CX001696CSRD VA I01 CX001999HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL103541HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL142603HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL142804HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R35HL145237NHLBI NIH HHS R01 HL142603NHLBI NIH HHS R01 HL142804NHLBI NIH HHS R35 HL145237NHLBI NIH HHS T32 HL007576U.S. Department of Veterans Affairs (VA) E9275-LU.S. Department of Veterans Affairs (VA) I01CX001696U.S. Department of Veterans Affairs (VA) I01CX007999
6 · The paper itself

Abstract

The impact of COVID-19 has been largely described after symptom development. Although the SARS-CoV-2 virus elevates heart rate (HR) prior to symptom onset, whether this virus evokes other presymptomatic alterations is unknown. This case study details the presymptomatic impact of COVID-19 on vascular and skeletal muscle function in a young woman [24 yr, 173.5 cm, 89 kg, body mass index (BMI): 29.6 kg·m

Indexed as

COVID-19Brachial ArteryCOVID-19 TestingFemaleHumansMuscle, SkeletalSARS-CoV-2blood flowendotheliummitochondriamuscle strengthSARS-CoV-2 virus

Identifiers

PMID34002634
PMCPMC8213510
OpenAlexW3161354074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.