Evidence map›Paper›PMID 34002286›Full record

ReviewAnnals of biomedical engineering2021

3D Printing for Cardiovascular Applications: From End-to-End Processes to Emerging Developments.

Ramtin Gharleghi, Claire A Dessalles, Ronil Lal, Sinead McCraith, Kiran Sarathy, Nigel Jepson, James Otton, Abdul I Barakat, Susann Beier

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

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  7. Advancements in Coronary Bifurcation Stenting Techniques: Insights From Computational and Bench Testing Studies.International journal for numerical methods in biomedical engineering · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Ramtin GharleghiFaculty of Engineering, School of Mechanical and Manufacturing, UNSW, Sydney, Australia.ORCID http://orcid.org/0000-0001-7478-2920
Claire A DessallesLadHyX - UMR 7646, École Polytechnique, Palaiseau, France.
Ronil LalFaculty of Engineering, School of Mechanical and Manufacturing, UNSW, Sydney, Australia.
Sinead McCraithFaculty of Engineering, School of Mechanical and Manufacturing, UNSW, Sydney, Australia.
Kiran SarathyPrince of Wales Hospital, Sydney, Australia.
Nigel JepsonPrince of Wales Hospital, Sydney, Australia.
James OttonDepartment of Cardiology, Liverpool Hospital, Sydney, Australia.
Abdul I BarakatLadHyX - UMR 7646, École Polytechnique, Palaiseau, France.
Susann BeierFaculty of Engineering, School of Mechanical and Manufacturing, UNSW, Sydney, Australia. s.beier@unsw.edu.au.
UNSW Sydney · AUÉcole Polytechnique · FRLiverpool Hospital · AUPrince of Wales Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3D printing as a means of fabrication has seen increasing applications in medicine in the last decade, becoming invaluable for cardiovascular applications. This rapidly developing technology has had a significant impact on cardiovascular research, its clinical translation and education. It has expanded our understanding of the cardiovascular system resulting in better devices, tools and consequently improved patient outcomes. This review discusses the latest developments and future directions of generating medical replicas ('phantoms') for use in the cardiovascular field, detailing the end-to-end process from medical imaging to capture structures of interest, to production and use of 3D printed models. We provide comparisons of available imaging modalities and overview of segmentation and post-processing techniques to process images for printing, detailed exploration of latest 3D printing methods and materials, and a comprehensive, up-to-date review of milestone applications and their impact within the cardiovascular domain across research, clinical use and education. We then provide an in-depth exploration of future technologies and innovations around these methods, capturing opportunities and emerging directions across increasingly realistic representations, bioprinting and tissue engineering, and complementary virtual and mixed reality solutions. The next generation of 3D printing techniques allow patient-specific models that are increasingly realistic, replicating properties, anatomy and function.

Indexed as

BioprintingHeartPrinting, Three-DimensionalTissue EngineeringHumansAdditive manufacturingBioprintingMedical technologyRapid prototypingTissue engineeringVirtual reality

Identifiers

PMID34002286
PMCPMC8648709
OpenAlexW3161845008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.