Evidence map›Paper›PMID 34002285›Full record

ArticleClinical and experimental medicine2022

Imbalance of circulating CTLA4

Yinmei Zhang, Mingmei Lin, Xinjie Hao, Muye Ping, Han Zhang, Jiajia Zheng

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical and experimental medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. B Cell Tolerance and Obstetric Antiphospholipid Syndrome.Clinical reviews in allergy & immunology · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yinmei ZhangDepartment of Laboratory Medicine, Peking University Third Hospital, Haidian District, No. 49 North Garden Road, Beijing, 100191, People's Republic of China.
Mingmei LinDepartment of Obstetrics and Gynecology, Peking University Third Hospital, Haidian District, No. 49 North Garden Road, Beijing, 100191, People's Republic of China.
Xinjie HaoDepartment of Laboratory Medicine, Peking University Third Hospital, Haidian District, No. 49 North Garden Road, Beijing, 100191, People's Republic of China.
Muye PingDepartment of Laboratory Medicine, Peking University Third Hospital, Haidian District, No. 49 North Garden Road, Beijing, 100191, People's Republic of China.
Han ZhangDepartment of Laboratory Medicine, Peking University Third Hospital, Haidian District, No. 49 North Garden Road, Beijing, 100191, People's Republic of China.
Jiajia ZhengDepartment of Laboratory Medicine, Peking University Third Hospital, Haidian District, No. 49 North Garden Road, Beijing, 100191, People's Republic of China. zhengjiajia@bjmu.edu.cn.ORCID http://orcid.org/0000-0003-3939-9875
Peking University · CN

Funding

National Natural Science Foundation of China 61771022National Natural Science Foundation of China 81873859
6 · The paper itself

Abstract

Obstetric antiphospholipid syndrome (OAPS) is a systemic autoimmune disease that is characterized clinically by a variety of obstetric manifestations (fetal death and recurrent abortions) and serologically by the presence of antiphospholipid antibodies (aPLs). Whether dysregulation of Follicular helper T (Tfh) and Follicular regulatory T (Tfr) cells contribute to the immunopathogenesis in OAPS is still unknown. We analyzed phenotypic characterizations of circulating Tfh cells and Tfr cells in OAPS patients and healthy individuals. CTLA4(Cytotoxic T lymphocyte antigen 4)

Indexed as

Antiphospholipid SyndromeT-Lymphocytes, RegulatoryComplement C4CTLA-4 AntigenHumansT-Lymphocytes, Helper-InducerComplement C4CTLA-4 AntigenCTLA4 protein, humanCTLA4OAPSTfh cellsTfr cells

Identifiers

PMID34002285
OpenAlexW3163351369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.