Evidence map›Paper›PMID 34002257›Full record

ArticleJournal of anesthesia2021

Predictors of one year chronic post-surgical pain trajectories following thoracic surgery.

Christopher W Liu, M Gabrielle Page, Aliza Weinrib, Dorothy Wong, Alexander Huang, Karen McRae, Joseph Fiorellino, Diana Tamir, Michael Kahn, Rita Katznelson and 9 more

Abstract read
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In one paragraph

Article in Journal of anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 2 countries.

Christopher W Liu *Department of Pain Medicine, Singapore General Hospital, Outram, Singapore.
M Gabrielle Page *Department of Anesthesiology and Pain Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada.
Aliza WeinribPain Research Unit and Transitional Pain Service, Department of Anesthesia, Toronto General Hospital, Toronto, ON, Canada.
Dorothy WongDepartment of Anesthesia and Pain Management, Toronto General Hospital, 200 Elizabeth Street, Toronto, ON, Canada.
Alexander HuangDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada.
Karen McRaeDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada.
Joseph FiorellinoDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada.
Diana TamirDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada.
Michael KahnDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada.
Rita KatznelsonDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada.
Karim LadhaDepartment of Anesthesia, St Michael's Hospital, Toronto, ON, Canada.
Faraj AbdallahDepartment of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, ON, Canada.
Marcelo CypelDivision of Thoracic Surgery, Toronto General Hospital, Toronto, ON, Canada.
Kazuhiro YasufukuDivision of Thoracic Surgery, Toronto General Hospital, Toronto, ON, Canada.
Vincent ChanDepartment of Anesthesiology and Pain Medicine, Toronto Western Hospital, Toronto, ON, Canada.
Monica ParryLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada.
James KhanDepartment of Anesthesiology, Mount Sinai Hospital, Toronto, ON, Canada.
Joel KatzDepartment of Psychology, York University, Toronto, ON, Canada.
Hance ClarkeDepartment of Anesthesiology and Pain Medicine, University of Toronto, Toronto, ON, Canada. hance.clarke@utoronto.ca.ORCID 0000-0003-4975-3823
University of Toronto · CAToronto General Hospital · CAMount Sinai Hospital · CAOttawa Hospital · CASingapore General Hospital · SGSt. Michael's Hospital · CAToronto Western Hospital · CAUniversité de Montréal · CAYork University · CA

Funding

CIHR
6 · The paper itself

Abstract

purposeChronic post-surgical pain (CPSP) is a highly prevalent complication following thoracic surgery. This is a prospective cohort study that aims to describe the pain trajectories of patients undergoing thoracic surgery beginning preoperatively and up to 1 year after surgery

methodsTwo hundred and seventy nine patients undergoing elective thoracic surgery were enrolled. Participants filled out a preoperative questionnaire containing questions about their sociodemographic information, comorbidities as well as several psychological and pain-related statuses. They were then followed-up during their immediate postoperative period and at the three, six and 12 month time-points to track their postoperative pain, complications and pain-related outcomes. Growth mixture modeling was used to construct pain trajectories.

resultsThe first trajectory is characterized by 185 patients (78.1%) with mild pain intensity across the 12 month period. The second is characterized by 32 patients (7.5%) with moderate pain intensity immediately after surgery which decreases markedly by 3 months and remains low at the 12 month follow-up. The final trajectory is characterized by 20 patients (8.4%) with moderate pain intensity immediately after surgery which persists at 12 months. Patients with moderate to severe postoperative pain intensity were much more likely to develop CPSP compared to patients with mild pain intensity. Initial pain intensity levels immediately following surgery as well as levels of pain catastrophizing at baseline were predicting pain trajectory membership. None of the surgical or anesthetic-related variables were significantly associated with pain trajectory membership.

conclusionPatients who undergo thoracic surgery can have postoperative pain that follows one of the three different types of trajectories. Higher levels of immediate postoperative pain and preoperative pain catastrophizing were associated with moderately severe CPSP.

Indexed as

Chronic PainThoracic SurgeryCatastrophizationHumansPain MeasurementPostoperative PainProspective StudiesChronic post-surgical painPain trajectoryPost-thoracotomy pain syndromeThoracic surgeryThoracotomy

Identifiers

PMID34002257
OpenAlexW3163277049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.