Evidence map›Paper›PMID 34002070›Full record

ReviewNature reviews. Urology2021

Machine learning for sperm selection.

Jae Bem You, Christopher McCallum, Yihe Wang, Jason Riordon, Reza Nosrati, David Sinton

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Observational
  13. Review
  14. [Progress in the application of artificial intelligence in assisted reproduction].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  15. Fresh versus frozen micro-TESE sperm and outcomes.Asian journal of andrology · 2025
    Review
  16. Article
  17. Review
  18. Review
  19. Assessment of Boar Semen Morphology and Morphometry.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jae Bem YouDepartment of Mechanical & Industrial Engineering, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-0385-2295
Christopher McCallumDepartment of Mechanical & Industrial Engineering, University of Toronto, Toronto, ON, Canada.
Yihe WangDepartment of Mechanical & Industrial Engineering, University of Toronto, Toronto, ON, Canada.
Jason RiordonDepartment of Mechanical & Industrial Engineering, University of Toronto, Toronto, ON, Canada.
Reza NosratiDepartment of Mechanical & Aerospace Engineering, Monash University, Clayton, VIC, Australia.ORCID http://orcid.org/0000-0002-1461-229X
David SintonDepartment of Mechanical & Industrial Engineering, University of Toronto, Toronto, ON, Canada. sinton@mie.utoronto.ca.ORCID http://orcid.org/0000-0003-2714-6408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infertility rates and the number of couples seeking fertility care have increased worldwide over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are being performed globally every year, but the success rate has remained at ~33%. Machine learning, an automated method of data analysis based on patterns and inference, is increasingly being deployed within the health-care sector to improve diagnostics and therapeutics. This technique is already aiding embryo selection in some fertility clinics, and has also been applied in research laboratories to improve sperm analysis and selection. Tremendous opportunities exist for machine learning to advance male fertility treatments. The fundamental challenge of sperm selection - selecting the most promising candidate from 10

Indexed as

Machine LearningSperm MotilityCell ShapeDNA DamageFertilization in VitroHumansInfertilityMaleSemen AnalysisSpermatozoaSperm Injections, IntracytoplasmicSperm Retrieval

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.