ArticleNature human behaviour2021
The natural selection of good science.
Article in Nature human behaviour, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Observer effect modulates classification in a quantum epistemic framework.Scientific reports · 2026Article
- An overview of contemporary theories of ageing.Nature cell biology · 2025Review
- Advancing longevity research through decentralized science.Frontiers in aging · 2024Article
- Impact of redefining statistical significance on P-hacking and false positive rates: An agent-based model.PloS one · 2024Article
- Replication of the natural selection of bad science.Royal Society open science · 2023Article
- Article
- Practical Methodological Reform Needs Good Theory.Perspectives on psychological science : a journal of the Association for Psychological Science · 2021Article
- Misinformation in and about science.Proceedings of the National Academy of Sciences of the United States of America · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scientists in some fields are concerned that many published results are false. Recent models predict selection for false positives as the inevitable result of pressure to publish, even when scientists are penalized for publications that fail to replicate. We model the cultural evolution of research practices when laboratories are allowed to expend effort on theory, enabling them, at a cost, to identify hypotheses that are more likely to be true, before empirical testing. Theory can restore high effort in research practice and suppress false positives to a technical minimum, even without replication. The mere ability to choose between two sets of hypotheses, one with greater prior chance of being correct, promotes better science than can be achieved with effortless access to the set of stronger hypotheses. Combining theory and replication can have synergistic effects. On the basis of our analysis, we propose four simple recommendations to promote good science.
Indexed as
Identifiers
34002054What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.