ArticleCommunications biology2021
Concurrent neuroimaging and neurostimulation reveals a causal role for dlPFC in coding of task-relevant information.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Cortical mapping of real-time ultrasound-imaging visual feedback for ankle dorsiflexion in patients after stroke: a fNIRS study.Journal of neuroengineering and rehabilitation · 2026Article
- Dynamic expectation strength and precision shape human pain perception through shared and dissociable α-oscillatory mechanisms.PLoS biology · 2026Article
- Article
- Consensus guidelines for the use of concurrent TMS-fMRI in cognitive and clinical neuroscience.Nature protocols · 2026Review
- White matter lesions associated with the reemergence of grasp reflexes in patients with idiopathic normal pressure hydrocephalus.Fluids and barriers of the CNS · 2025Article
- Forewarned Is Forearmed: The Single- and Dual-Brain Mechanisms in Detectors from Dyads of Varying Social Distance during Deceptive Outcome Evaluation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Representation of top-down versus bottom-up attention in the right dorsolateral prefrontal cortex and superior parietal lobule.Behavioral and brain functions : BBF · 2025Article
- Transcranial magnetic stimulation to left VLPFC or right DLPFC promotes forgetting in working memory.Psychological medicine · 2025Article
- Distinct neurochemical predictors for different phases of decision-making learning.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Neural evidence that humans reuse strategies to solve new tasks.PLoS biology · 2025Article
- Domain general frontoparietal regions show modality-dependent coding of auditory and visual rules.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Unveiling Cognitive Interference: fNIRS Insights Into Poststroke Aphasia During Stroop Tasks.Neural plasticity · 2025Article
- Selective Attention and Decision-Making Have Separable Neural Bases in Space and Time.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Chronometric TMS-fMRI of personalized left dorsolateral prefrontal target reveals state-dependency of subgenual anterior cingulate cortex effects.Molecular psychiatry · 2024Article
- Information-based TMS to mid-lateral prefrontal cortex disrupts action goals during emotional processing.Nature communications · 2024Article
- Orthogonal neural encoding of targets and distractors supports multivariate cognitive control.Nature human behaviour · 2024Article
- Effects of transcranial magnetic stimulation on the human brain recorded with intracranial electrocorticography.Molecular psychiatry · 2024Article
- Interleaved TMS/fMRI shows that threat decreases dlPFC-mediated top-down regulation of emotion processing.NPP - digital psychiatry and neuroscience · 2024Article
- Disentangling the neural correlates of semantic and domain-general control: The roles of stimulus domain and task process.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Prefrontal Cortex Codes Representations of Target Identity and Feature Uncertainty.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
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Authors and funding
5 authors.
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Abstract
Dorsolateral prefrontal cortex (dlPFC) is proposed to drive brain-wide focus by biasing processing in favour of task-relevant information. A longstanding debate concerns whether this is achieved through enhancing processing of relevant information and/or by inhibiting irrelevant information. To address this, we applied transcranial magnetic stimulation (TMS) during fMRI, and tested for causal changes in information coding. Participants attended to one feature, whilst ignoring another feature, of a visual object. If dlPFC is necessary for facilitation, disruptive TMS should decrease coding of attended features. Conversely, if dlPFC is crucial for inhibition, TMS should increase coding of ignored features. Here, we show that TMS decreases coding of relevant information across frontoparietal cortex, and the impact is significantly stronger than any effect on irrelevant information, which is not statistically detectable. This provides causal evidence for a specific role of dlPFC in enhancing task-relevant representations and demonstrates the cognitive-neural insights possible with concurrent TMS-fMRI-MVPA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.