ArticleScientific reports2021
The epidemiology of fracture-related infections in Germany.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07582575 (Nutrition and Trauma), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nutrition and Trauma (NuTra) - The Influence of Malnutrition in Geriatric Trauma Patients
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of Negative-Pressure Wound Therapy in Patients with Fracture-Related Infection: A Systematic Review and Critical Appraisal.BioMed research international · 2021Pooled it
- [Advances on limb reconstruction technology for bone infection].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Epidemiology and healthcare burden of implant-associated complications in Germany: a nationwide population-based analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Impact of Infection Timing on Outcomes: A Comparative Study of Periprosthetic Joint and Fracture-Related Infections.Orthopaedic surgery · 2026Article
- Incidence and risk factors of fracture-related infection after SIGN nailing of open femoral fractures in Ethiopia.Scientific reports · 2026Article
- [Zeta-focal bone lengthening for bone defects after fracture-related infection: a two-case based research].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Article
- Negative Pressure Wound Therapy and Ultrasound Monitoring for Fracture-Related Infection of the Proximal Femur: A Case Report.Infection and drug resistance · 2026Article
- Sonication fluid cultures enhance pathogen identification in fracture-related-infection (FRI).Journal of bone and joint infection · 2026Article
- Life after bone infection: a retrospective comparison of quality of life in patients with periprosthetic joint infection and fracture-related infections.Journal of orthopaedic surgery and research · 2025Article
- [Osteosynthesis of subtrochanteric femoral fractures in adults].Chirurgie (Heidelberg, Germany) · 2025Article
- Safety and complications of antimicrobial coated compared to conventional intramedullary femoral nails in proximal femoral fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Observational
- Effective detection of staphylococcal infections in human bone tissue using combined raman microscopy and micro-computed tomography.Frontiers in bioengineering and biotechnology · 2025Article
- Future directions for early detection of fracture related infections.Journal of orthopaedics · 2024Article
- Pathogens in FRI - Do bugs matter? - An analysis of FRI studies to assess your enemy.Journal of orthopaedics · 2024Article
- Time to Positivity in Blood Culture Bottles Inoculated with Sonication Fluid from Fracture-Related Infections.Microorganisms · 2024Article
- Fracture related Infection - Challenges in definition and diagnosis.Journal of orthopaedics · 2024Article
- Fracture-Related Infection-Epidemiology, Etiology, Diagnosis, Prevention, and Treatment.Deutsches Arzteblatt international · 2024Review
- Acute prophylactic antibiotic nailing of open femoral shaft fractures for prevention of fracture-related infection.Proceedings (Baylor University. Medical Center) · 2024Article
- Treatment of Fracture-Related Infection after Pelvic Fracture.Journal of clinical medicine · 2023Article
- [Antibiotic use for prophylaxis and empirical therapy of fracture-related infections in Germany : A survey of 44 hospitals].Unfallchirurgie (Heidelberg, Germany) · 2023Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The epidemiology of fracture-related infection (FRI) is unknown, which makes it difficult to estimate future demands and evaluate progress in infection prevention. Therefore, we aimed to determine the nationwide burden's development over the last decade as a function of age group and gender. FRI prevalence as a function of age group and gender was quantified based on annual ICD-10 diagnosis codes from German medical institutions between 2008 through 2018, provided by the Federal Statistical Office of Germany (Destatis). The prevalence of FRI increased by 0.28 from 8.4 cases per 100,000 inhabitants to 10.7 cases per 100,000 inhabitants between 2008 and 2018. The proportion of fractures resulting in FRI increased from 1.05 to 1.23%. Gender distribution was equal. Patients aged 60-69 years and 70-79 years comprised the largest internal proportion with 20.2% and 20.7%, respectively, whereby prevalence increased with age group. A trend towards more diagnoses in older patients was observed with a growth rate of 0.63 for patients older than 90 years. Increasing rates of fracture-related infection especially in older patients indicate an upcoming challenge for stakeholders in health care systems. Newly emerging treatment strategies, prevention methods and interdisciplinary approaches are strongly required.
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