SynthesisScientific reports2021
Ultrasound-guided corticosteroid injection for patients with carpal tunnel syndrome: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Comparing the efficacy of ultrasound-guided versus anatomical localization for corticosteroid injection in the treatment of carpal tunnel syndrome: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2025Pooled it
- Pooled it
- Pooled it
- Injection therapy for carpal tunnel syndrome: A systematic review and network meta-analysis of randomized controlled trials.PloS one · 2024Pooled it
- Use of Iontophoresis with Corticosteroid in Carpal Tunnel Syndrome: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Local injection therapy for carpal tunnel syndrome: a network meta-analysis of randomized controlled trial.Frontiers in pharmacology · 2023Pooled it
- Efficacy of Perineural Dextrose Versus Corticosteroid Injection for Carpal Tunnel Syndrome: A Randomized, Double-Blind Clinical Trial.Muscle & nerve · 2026Trial
- Ultrasound-guided versus landmark-guided corticosteroid injections for carpal tunnel syndrome: an overview and cross-sectional analysis of overlapping meta-analyses of randomized controlled trials.European radiology · 2026Article
- Review
- Perineural Steroid Injections in Cubital Tunnel Syndrome: A Systematic Review and Meta-Analysis.Cureus · 2026Review
- Standardized High-Resolution Ultrasound Protocol for the Diagnosis and Monitoring of Carpal Tunnel Syndrome: A Mixed-Design Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
- Ultrasound guided procedures in the musculoskeletal system: a narrative review with illustrative examples.Quantitative imaging in medicine and surgery · 2024Review
- Carpal Tunnel Syndrome: Neuropathic Pain Associated or Not with a Nociplastic Condition.Biomedicines · 2023Article
- Application of a nerve stereoscopic reconstruction technique based on ultrasonic images in the diagnosis of neuralgic amyotrophy.Frontiers in physiology · 2023Article
- Use of Sonophoresis with Corticosteroids in Carpal Tunnel Syndrome: Systematic Review and Meta-Analysis.Journal of personalized medicine · 2022Review
- The outcomes of carpal tunnel decompression based on electro-diagnostic approaches and clinical symptoms in patients suffering from carpal tunnel syndrome (CTS).Journal of family medicine and primary care · 2022Article
- Update on Efficacy of Conservative Treatments for Carpal Tunnel Syndrome.Journal of clinical medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carpal tunnel syndrome (CTS) refers to the symptoms and signs caused by the compression of the median nerve in the carpal tunnel. It can be treated by corticosteroid injection into the carpal tunnel. Two methods for injection have been employed, namely ultrasound-guided and landmark-guided injection. This systematic review and meta-analysis was conducted to compare these methods in terms of several outcomes. A search of the PubMed, Cochrane Library, and Embase databases was performed from the date of their inception to October 7, 2020 to identify randomized controlled trials (RCTs). Results for continuous variables are expressed as standardized mean differences (SMDs) with 95% confidence intervals (CIs). Analyses were performed using RevMan 5.3 software. The analysis included eight RCTs published between 2013 and 2019 with a total of 448 patients. Ultrasound-guided injection yielded more favorable results than landmark-guided injection for the Boston Carpal Tunnel Syndrome Questionnaire, Symptom Severity Scale [SMD = - 0.43, 95% CI (- 0.68, - 0.19), P = 0.0005] and Boston Carpal Tunnel Syndrome Questionnaire, Functional Status Scale [SMD = - 0.50, 95% CI (- 0.84, - 0.15), P = 0.005]. Ultrasound-guided corticosteroid injection is recommended for patients with CTS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.