ArticleScientific reports2021
Dietary source of polyunsaturated fatty acids influences cell cytotoxicity in broiler chickens.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Effects of graded dietary levels of microalgae on growth performance, fatty acid composition, and meat quality in broilers.Poultry science · 2026Article
- Effect of Omega-3 Fatty Acid Supplementation on Broilers' Health and Meat Quality-Systematic Review.Animals : an open access journal from MDPI · 2026Review
- Flaxseeds and thymol feed as dietary supplementation for Caiman latirostris: effects on immune status, meat quality and intestinal morphology.Tropical animal health and production · 2025Article
- Review
- Oxidative Stress in Poultry and the Therapeutic Role of Herbal Medicine in Intestinal Health.Antioxidants (Basel, Switzerland) · 2024Review
- Insights into the gut microbiota characteristics between the organic and traditional feeding chickens based on amplicon and metagenomic sequencing.Frontiers in microbiology · 2024Article
- Seasonal changes in diet, immune function, and oxidative stress in three passerines inhabiting a Mediterranean climate.Oecologia · 2023Article
- Performance and antioxidant traits of broiler chickens fed with diets containing rapeseed or flaxseed oil and optimized quercetin.Scientific reports · 2023Article
- The Variety of Applications ofBiology · 2022Review
- Effect of Ginger Powder on Production Performance, Antioxidant Status, Hematological Parameters, Digestibility, and Plasma Cholesterol Content in Broiler Chickens.Animals : an open access journal from MDPI · 2022Article
- The relation between avian coronaviruses and SARS-CoV-2 coronavirus.Frontiers in microbiology · 2022Review
- Dietary Supplementation of Fructooligosaccharides Enhanced Antioxidant Activity and Cellular Immune Response in Broiler Chickens.Frontiers in veterinary science · 2022Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study aims to investigate the effects of dietary source of n-3 polyunsaturated fatty acids (PUFA) on immune response in broiler chickens, represented by cytotoxic cell activity. A total of 255 one-day-old male Cobb 500 broiler chickens were fed on fish oil (FO)-, flaxseed oil-enriched diets at 50 and 19 g/kg, respectively, in addition to the soybean-based control diet. At slaughter, samples of blood and spleen were harvested from 20 birds/treatment (n = 20). The immune tissues' fatty acid profile was analyzed by gas chromatography, and the cytotoxic cell activity was investigated. The results showed that supplementing broiler chickens with diets rich in n-3 PUFA had a substantial effect on the broiler immune tissues' fatty acid profile. Cytotoxic cell activity was significantly higher in splenocytes and peripheral blood mononuclear cells (PBMCs) from broilers fed flaxseed oil than those provided FO and the soybean control diet. These results suggest that flaxseed oil may be used to enrich chickens with n-3 PUFA and improve the immune status of chicken flocks to resist diseases.
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